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Multiscale Mechanobiology of Bone Remodeling and Adaptation

  • Book
  • © 2018

Overview

Editors:
  1. Peter Pivonka

    1. Biomedical Engineering & Spinal Disorder, Queensland University of Technology, Brisbane, Australia

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  • Presents state-of-the art developments in multiscale modeling
  • Includes latest experimental data on multiscale mechanobiology of bone remodeling and adaptation
  • Contributions are from experts from applied mechanics, bone biology, and material science
  • Includes supplementary material: sn.pub/extras

Part of the book series: CISM International Centre for Mechanical Sciences (CISM, volume 578)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-xii
    Download chapter PDF

  2. Functional Adaptation of Bone: The Mechanostat and Beyond

    • Peter Pivonka, Aaron Park, Mark R. Forwood
    Pages 1-60

  3. Application of Disease System Analysis to Osteoporosis: From Temporal to Spatio-Temporal Assessment of Disease Progression and Intervention

    • Silvia Trichilo, Peter Pivonka
    Pages 61-121

  4. Musculoskeletal Modelling and the Physiome Project

    • Justin Fernandez, Ju Zhang, Vickie Shim, Jacob T. Munro, Massimo Sartori, Thor Besier et al.
    Pages 123-174

  5. Review of “Universal” Rules Governing Bone Composition, Organization, and Elasticity Across Organizational Hierarchies

    • Viktoria Vass, Claire Morin, Stefan Scheiner, Christian Hellmich
    Pages 175-229

  6. Computational Biomechanics of Bone Adaptation by Remodeling

    • Taiji Adachi, Yoshitaka Kameo
    Pages 231-257

  7. Biology of Bone and the Interaction of Bone with Other Organ Systems

    • David M. Findlay
    Pages 259-287
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Keywords

About this book

The book presents state-of-the-art developments in multiscale modeling and latest experimental data on multiscale mechanobiology of bone remodeling and adaptation including fracture healing applications. The multiscale models include musculoskeletal models describing bone-muscle interactions during daily activities such as walking or running, micromechanical models for estimation of bone mechanical properties, bone remodeling and adaptation models, cellular models describing the complex bone-cell interactions taking into account biochemical and biomechanical regulatory factors.
Also subcellular processes are covered including arrangement of actin filaments due to mechanical loading and change of receptor configurations.

Editors and Affiliations

  • Biomedical Engineering & Spinal Disorder, Queensland University of Technology, Brisbane, Australia

    Peter Pivonka

Bibliographic Information

  • Book Title: Multiscale Mechanobiology of Bone Remodeling and Adaptation

  • Editors: Peter Pivonka

  • Series Title: CISM International Centre for Mechanical Sciences

  • DOI: https://doi.org/10.1007/978-3-319-58845-2

  • Publisher: Springer Cham

  • eBook Packages: Engineering, Engineering (R0)

  • Copyright Information: CISM International Centre for Mechanical Sciences 2018

  • Hardcover ISBN: 978-3-319-58843-8Published: 03 July 2017

  • Softcover ISBN: 978-3-319-86489-1Published: 10 August 2018

  • eBook ISBN: 978-3-319-58845-2Published: 20 June 2017

  • Series ISSN: 0254-1971

  • Series E-ISSN: 2309-3706

  • Edition Number: 1

  • Number of Pages: XII, 287

  • Number of Illustrations: 98 b/w illustrations

  • Topics: Solid Mechanics, Biomaterials, Orthopedics

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