Editors:
- This book will evaluate the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold-standard to define radiological resistance
- This book will describe the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment
- This book will help determine the role of the cancer stem cell phenotype in resistance
- This book will review the experimental models to study resistance
- This book will address new approaches to overcome resistance to sorafenib, using successful examples from other malignancies
Part of the book series: Resistance to Targeted Anti-Cancer Therapeutics (RTACT, volume 13)
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Table of contents (8 chapters)
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Front Matter
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Back Matter
About this book
This volume evaluates the clinical patterns of resistance to sorafenib, the impact of trial design in the second-line setting and the current gold standard to define radiological resistance; describes the molecular mechanisms responsible for treatment resistance in HCC patients, including components of the immune system and tumor microenvironment; determines the role of the cancer stem cell phenotype in resistance; reviews the experimental models to study resistance; and addresses new approaches to overcome resistance to sorafenib, using successful examples from other malignancies.
Editors and Affiliations
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Division of Liver Diseases, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, Graduate School of Biomedical Sciences, New York, USA
Augusto Villanueva
About the editor
Bibliographic Information
Book Title: Resistance to Molecular Therapies for Hepatocellular Carcinoma
Editors: Augusto Villanueva
Series Title: Resistance to Targeted Anti-Cancer Therapeutics
DOI: https://doi.org/10.1007/978-3-319-56197-4
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Hardcover ISBN: 978-3-319-56196-7Published: 27 July 2017
Softcover ISBN: 978-3-319-85850-0Published: 02 August 2018
eBook ISBN: 978-3-319-56197-4Published: 14 July 2017
Series ISSN: 2196-5501
Series E-ISSN: 2196-551X
Edition Number: 1
Number of Pages: XIII, 147
Number of Illustrations: 16 illustrations in colour
Topics: Cancer Research