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Development of In Vitro Maturation for Human Oocytes

Natural and Mild Approaches to Clinical Infertility Treatment

  • Book
  • © 2017

Overview

Editors:
  1. Ri-Cheng Chian

    1. McGill University, Longueuil, Canada

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  2. Geeta Nargund

    1. St. George's Hospital, London, United Kingdom

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  3. Jack Y. J. Huang

    1. Stanford University, Palo Alto, USA

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  • Focuses exclusively on the techniques used in natural and mild stimulation for in vitro fertilization (IVF) and in vitro maturation (IVM) for the clinical treatment of infertility

  • Describes how these techniques are safer, more cost-effective and more accessible for the developing world than traditional IVF

  • Written and edited by an international array of thought leaders and expert clinicians in IVF and infertility treatment

  • Includes supplementary material: sn.pub/extras

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Table of contents (27 chapters)

  1. Front Matter

    Pages i-xvii
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  2. Ovarian Function

    1. Front Matter

      Pages 1-1
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    2. Ovarian Endocrinology

      • Seido Takae, Nao Suzuki
      Pages 3-35

    3. Follicular Development and Oocyte Growth

      • Han Li, Ri-Cheng Chian
      Pages 37-57

    4. A New Understanding on the Regulation of Oocyte Meiotic Prophase Arrest and Resumption

      • Meijia Zhang
      Pages 59-74

    5. Mitochondria of the Oocyte

      • Yoshiharu Morimoto, Shu Hashimoto, Takayuki Yamochi, Hiroya Goto, Ami Amo, Masaya Yamanaka et al.
      Pages 75-91

  3. Natural Cycle IVF and Stimulated Cycle IVF

    1. Front Matter

      Pages 93-93
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    2. Natural Cycle IVF: Summary of the Current Literature

      • Sabine Roesner, Thomas Strowitzki
      Pages 95-104

    3. Follicular Fluid Hormone Profiles in Natural Cycle IVF Patients During Follicular Phase

      • N. Ellissa Baskind, Vinay Sharma
      Pages 105-128

    4. Standard Ovarian Stimulation Protocols and Their Outcomes

      • Suchada Mongkolchaipak
      Pages 129-146

    5. Which Women Are Suitable for Natural and Modified Natural Cycle IVF?

      • A. K. Datta, B. Deval, S. Campbell, G. Nargund
      Pages 147-155

    6. Natural Cycle IVF with Spontaneous LH Surge

      • Daniel Bodri
      Pages 157-173

    7. Risk Factors and Preventive Measures of Ovarian Hyperstimulation Syndrome

      • Byung-Chul Jee
      Pages 175-184

    8. Prevention and Management of OHSS

      • Meera Sridhar Shah, Jack Y.J. Huang
      Pages 185-191

  4. Minimal or Mild Stimulation for IVF

    1. Front Matter

      Pages 193-193
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    2. Minimal or Mild Ovarian Stimulation for IVF: Overview

      • A.K. Datta, S. Campbell, G. Nargund
      Pages 195-209

    3. Cumulative Pregnancy Rates After Six Cycles of Modified Natural Cycle IVF

      • M. J. Pelinck, A. E. P. Cantineau, J. van Echten-Arends
      Pages 211-226

    4. Minimal Stimulation for IVF with Clomiphene Citrate

      • Keiichi Kato
      Pages 227-235

    5. Mild Stimulation Protocols: Combination of Clomiphene Citrate and Recombinant FSH or HMG

      • Jiayin Liu, Wei Wu
      Pages 237-247

    6. Mild Stimulation Protocol for Poor Ovarian Responders Undergoing IVF

      • Alberto Revelli, Simona Casano, Chiara Benedetto
      Pages 249-255
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Keywords

About this book

An ideal reference for infertility specialists and reproductive endocrinologists alike, this comprehensive text discusses current natural and mild approaches to in vitro fertilization (IVF) and the development of in vitro maturation (IVM) as a clinical treatment. It is divided thematically into four sections. Part I presents the basic science of ovarian endocrinology and the mechanism of oocyte maturation, including follicular development and the importance of mitochondrial changes. The differences between natural cycle IVF and stimulated IVF are presented in part II, including the standard ovarian stimulation protocols and their outcomes and the etiology, prevention and management of ovarian hyperstimulation syndrome (OHSS). Minimal and mild stimulation for IVF is discussed in part III, including mild stimulation protocols for oncofertility patients and the new minimally invasive INVO procedure. In vitro maturation as a clinical treatment is the subject of part IV, discussing the methodology of immature oocyte retrieval as well as other laboratory aspects and congenital and obstetrical outcomes of babies born from IVM.

Combining expertise from thought leaders around the world, Development of In Vitro Maturation for Human Oocytes will be a go-to resource for infertility researchers and practitioners and reproductive endocrinologists working with infertile couples looking for safer and more cost-effective options for treatment.

Editors and Affiliations

  • McGill University, Longueuil, Canada

    Ri-Cheng Chian

  • St. George's Hospital, London, United Kingdom

    Geeta Nargund

  • Stanford University, Palo Alto, USA

    Jack Y. J. Huang

About the editors

Ri-Cheng Chian, MSc, PhD, Associate Professor, Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada

Geeta Nargund FRCOG, Medical Director, Create Fertility, Lead consultant in Reproductive Medicine, St George's Hospital NHS Trust, President, International Society for Mild Approaches in Assisted Reproduction (ISMAAR), London, UK

Jack Y. J. Huang, MD, PhD, Assistant Professor, Stanford University School of Medicine, Director, International Patients Program and Stanford Fertility and Reproductive Medicine In Vitro Fertilization Program, Stanford University Medical Center, Stanford, CA, USA


Bibliographic Information

  • Book Title: Development of In Vitro Maturation for Human Oocytes

  • Book Subtitle: Natural and Mild Approaches to Clinical Infertility Treatment

  • Editors: Ri-Cheng Chian, Geeta Nargund, Jack Y. J. Huang

  • DOI: https://doi.org/10.1007/978-3-319-53454-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-53452-7Published: 23 May 2017

  • Softcover ISBN: 978-3-319-85157-0Published: 28 July 2018

  • eBook ISBN: 978-3-319-53454-1Published: 10 May 2017

  • Edition Number: 1

  • Number of Pages: XVII, 376

  • Number of Illustrations: 11 b/w illustrations, 56 illustrations in colour

  • Topics: Reproductive Medicine, Endocrinology

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