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Male Hypogonadism

Basic, Clinical and Therapeutic Principles

  • Book
  • © 2017

Overview

Editors:
  1. Stephen J. Winters

    1. Department of Medicine, Endocrinology, D, University of Louisville Health Sciences, Louisville, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Ilpo T. Huhtaniemi

    1. Department of Surgery and Cancer, Imperial College London, London, United Kingdom

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • A revised and updated edition of the classic 2004 text on the etiology, diagnosis and treatment of male hypogonadism
  • Discusses both normal and abnormal testicular function and hypogonadism due to genetic causes, environmental factors, pre-existing conditions, obesity and other metabolic issues, and aging
  • Presents the latest clinical information on androgen replacement therapy and spermatogenesis stimulation
  • Includes supplementary material: sn.pub/extras

Part of the book series: Contemporary Endocrinology (COE)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Neuroendocrine Control of Human Testicular Function

    • Joseph P. Moore Jr., Stephen J. Winters
    Pages 1-24

  3. The Human Leydig Cell

    • Peter J. O’Shaughnessy
    Pages 25-47

  4. Human Spermatogenesis and Its Regulation

    • Haiqi Chen, Dolores Mruk, Xiang Xiao, C. Yan Cheng
    Pages 49-72

  5. Normal and Delayed Puberty

    • Sasha Howard, Leo Dunkel
    Pages 73-93

  6. Congenital Hypogonadotropic Hypogonadism in Males: Clinical Features and Pathophysiology

    • Ravikumar Balasubramanian, William F. Crowley Jr.
    Pages 95-126

  7. Male Hypogonadism Resulting from Mutations in the Genes for the Gonadotropin Subunits and Their Receptors

    • Ilpo T. Huhtaniemi
    Pages 127-152

  8. Hypogonadism in Males with Congenital Adrenal Hyperplasia

    • Nike M. M. L. Stikkelbroeck, Hedi L. Claahsen-van der Grinten
    Pages 153-167

  9. Male Hypogonadism Due to Disorders of the Pituitary and Suprasellar Region

    • Rosario Pivonello, Ciro Salzano, Mariano Galdiero, Annamaria Colao
    Pages 169-186

  10. Klinefelter Syndrome and Other Forms of Primary Testicular Failure

    • John K. Amory, William J. Bremner
    Pages 187-196

  11. The Undescended Testis

    • Peter A. Lee, Christopher P. Houk, Jorma Toppari
    Pages 197-217

  12. Male Hypogonadism and Liver Disease

    • Samuel M. Kim, Swaytha Yalamanchi, Adrian S. Dobs
    Pages 219-234

  13. Male Hypogonadism Due to Cancer and Cancer Treatments

    • Rod T. Mitchell, Jan-Bernd Stukenborg, Kirsi Jahnukainen
    Pages 235-256

  14. Exercise and Male Hypogonadism: Testosterone, the Hypothalamic-Pituitary-Testicular Axis, and Exercise Training

    • Anthony C. Hackney, Travis Anderson, Jennifer Dobridge
    Pages 257-280

  15. Environmental Causes of Testicular Dysfunction

    • Richard M. Sharpe
    Pages 281-304

  16. Sex Hormone-Binding Globulin and the Metabolic Syndrome

    • Geoffrey L. Hammond
    Pages 305-324

  17. An Ensemble Perspective of Aging-Related Hypoandrogenemia in Men

    • Peter Y. Liu, Paul Takahashi, Johannes D. Veldhuis
    Pages 325-347

  18. Obesity and Aging in Late-Onset Hypogonadism

    • Giulia Rastrelli, Frederick C. W. Wu
    Pages 349-366

  19. Androgen Replacement Therapy in Hypogonadal Men

    • Jonas Čeponis, Ronald S. Swerdloff, Christina Wang
    Pages 367-397

  20. Androgen Therapy for Hypogonadism in Men with Chronic Illnesses

    • Wenyi Zhang, Moizza Shabbir, Peter Y. Liu
    Pages 399-422
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Keywords

About this book

Now in a revised second edition, this comprehensive text covers all aspects of male hypogonadism from the basic science to clinical management, comprehensively explaining and applying new insights to the treatment of hypogonadal men. Chapters covering neuroendocrine control of testicular function, Leydig cell function, spermatogenesis, and normal and delayed puberty open the book. The focus then turns to the pathophysiology and treatment of hypogonadism and other forms of testicular dysfunction, such as Klinefelter syndrome, cryptorchidism, and disorders of the pituitary, as well as reproductive and endocrine consequences of cancer treatment, environmental factors, obesity and aging. Next are chapters that describe the available options for androgen replacement therapy, and the outcomes when men with hypogonadism of various causes are treated with testosterone, as well as a chapter devoted to current approaches to stimulating spermatogenesis in gonadotropin-deficient men. 

Highly practical and updated with the latest available data, this second edition of Male Hypogonadism: Basic, Clinical and Therapeutic Principles cogently presents a large body of scientific information on male reproductive endocrinology to provide a thorough understanding of the pathophysiology, clinical characteristics, and treatments for disorders that adversely affect testicular function.

Editors and Affiliations

  • Department of Medicine, Endocrinology, D, University of Louisville Health Sciences, Louisville, USA

    Stephen J. Winters

  • Department of Surgery and Cancer, Imperial College London, London, United Kingdom

    Ilpo T. Huhtaniemi

About the editors

Stephen J. Winters, MD, Professor of Medicine, Chief, Division of Endocrinology, Metabolism and Diabetes, University of Louisville, Louisville, KY, USA

Ilpo Huhtaniemi, MD, PhD, Professor Emeritus of Reproductive Endocrinology, Institute of Reproductive and Developmental Biology, Department of Surgery & Cancer, Imperial College London, Hammermith Campus, London, UK

Bibliographic Information

  • Book Title: Male Hypogonadism

  • Book Subtitle: Basic, Clinical and Therapeutic Principles

  • Editors: Stephen J. Winters, Ilpo T. Huhtaniemi

  • Series Title: Contemporary Endocrinology

  • DOI: https://doi.org/10.1007/978-3-319-53298-1

  • Publisher: Humana Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2017

  • Hardcover ISBN: 978-3-319-53296-7Published: 08 May 2017

  • Softcover ISBN: 978-3-319-85119-8Published: 25 July 2018

  • eBook ISBN: 978-3-319-53298-1Published: 25 April 2017

  • Series ISSN: 2523-3785

  • Series E-ISSN: 2523-3793

  • Edition Number: 2

  • Number of Pages: XIV, 446

  • Number of Illustrations: 48 b/w illustrations, 42 illustrations in colour

  • Topics: Endocrinology, Andrology, Reproductive Medicine

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