Graphene-based Materials in Health and Environment

1. Front Matter

   Pages i-ix

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2. Medicine: Nanomedicine

   1. Front Matter

      Pages 1-1

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   2. Potential and Challenges of Graphene in Medicine

      • Marta Skoda, Ilona Dudek, Dariusz Szukiewicz

      Pages 3-33

   3. Graphene-Based Materials in Biosensing, Bioimaging, and Therapeutics

      • Sivaramapanicker Sreejith, Hrishikesh Joshi, Yanli Zhao

      Pages 35-61

3. Medicine: Biosensors

   1. Front Matter

      Pages 63-63

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   2. Hybrid Graphene Metallic Nanoparticles for Biodetection

      • Manos Gkikas

      Pages 65-100

4. Medicine: Tissue Engineering

   1. Front Matter

      Pages 101-101

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   2. Stem Cells Commitment on Graphene-Based Scaffolds

      • Maurizio Buggio, Marco Tatullo, Stefano Sivolella, Chiara Gardin, Letizia Ferroni, Eitan Mijiritsky et al.

      Pages 103-133

   3. Graphene: An Emerging Carbon Nanomaterial for Bone Tissue Engineering

      • Nileshkumar Dubey, Fanny Esther Denise Decroix, Vinicius Rosa

      Pages 135-158

   4. Potentiality of Graphene-Based Materials for Neural Repair

      • María Teresa Portolés, María Concepción Serrano

      Pages 159-190

   5. Graphene-Based Smart Nanomaterials: Novel Opportunities for Biology and Neuroengineering

      • Antonina M. Monaco, Michele Giugliano

      Pages 191-218

   6. Stimulus Responsive Graphene Scaffolds for Tissue Engineering

      • Sofia S. Almeida, André F. Girão, Gil Gonçalves, António Completo, P. A. A. P. Marques

      Pages 219-256

5. Environment

   1. Front Matter

      Pages 257-257

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   2. Graphene Hybrid Architectures for Chemical Sensors

      • Parikshit Sahatiya, Sushmee Badhulika

      Pages 259-285

   3. Antimicrobial Properties of Graphene Nanomaterials: Mechanisms and Applications

      • Adel Soroush, Douglas Rice, Md Saifur Rahaman, François Perreault

      Pages 287-322

   4. Toxicity and Environmental Applications of Graphene-Based Nanomaterials

      • Enrico Tapire Nadres, Jingjing Fan, Debora Frigi Rodrigues

      Pages 323-356

This book provides a comprehensive overview of the potential use of graphene-based materials in two important societal areas: medicine and the environment. It discusses how new graphene-based materials can be creatively used for biological purposes, for example as delivery vehicles for diagnostics or therapeutics, ultrasensitive sensors, smart responsive substrates for artificial-tissue design and biomarkers. Moreover, it presents new insights into their use as sorbent or photocatalytic materials for environmental decontamination in water and gas-phase desalination membranes and as sensors for contaminant monitoring, giving relevance to the current discussions on the possible toxicological effects of graphene-based materials.

• Desalination membranes
• Graphene catalystis
• Graphene foams
• Graphene macrostructures
• Water purification
• water quality and water pollution

• Nanoengineering Research Division, Department of Mechanical Engineering, Centre for Mechanical Technology and Automation, University of Aveiro, Aveiro, Portugal

  Gil Gonçalves , Paula Marques, Mercedes Vila

Gil Gonçalves graduated in 2003 in Chemistry and obtained a Master’s degree in Materials Science in 2008 from the University of Aveiro (Portugal). In 2012 he received his Ph.D in Mechanical Engineering from the Center for Mechanical Technology and Automation (TEMA) University of Aveiro (UA), where he then pursued research on the development of graphene nanocomposites for biomedical and environmental applications until 2016. After obtaining a Marie Curie research fellowship, he started working at the Institute of Material Science of Barcelona-High Council of Spanish Research (ICMAB-CSIC) on the development of ultra-sensitive nanotherapeutic anticancer agents. Currently, he is also a member of the editorial board of Nature Publishing Group’s Scientific Reports in the field of chemical physics.


Mercedes Vila is currently the scientific director of Coating Technologies S.L. and guest assistant professor at the University of Aveiro’s Mechanical Engineering Department TEMA Research Unit. Her main research interests focus on the surface modification and functionalization of materials and materials behavior under different environments, e.g. biomaterials–cell interactions under physical stimuli, tribological responses and environmental remediation.


Paula Marques is a principal investigator in the Nanoengineering Group of TEMA research unit at the University of Aveiro. Paula’s research interests are related to the engineering and development of new, nanostructured materials that may offer solutions to societal problems. She started working with carbon nanostructures in 2007, and has been exploring the potential of graphene oxide for health and environmental applications since 2010, with the aim of engineering solutions that foster a cleaner, healthier, safer and more sustainable world.

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