Editors:
- Provides a comprehensive overview on the role of the BBB during CNS inflammation
- Covers inflammatory diseases, like autoimmune and viral induced CNS inflammation, cerebral malaria, multiple sclerosis, bacterial meningitis, and others
- Presents methods to study neuro-inflammation, employing BBB animal models and imaging techniques
Part of the book series: Progress in Inflammation Research (PIR)
Buy it now
Buying options
Tax calculation will be finalised at checkout
Other ways to access
This is a preview of subscription content, log in via an institution to check for access.
Table of contents (11 chapters)
-
Front Matter
-
Back Matter
About this book
This PIR volume presents a comprehensive collection of reviews that focus on the role of the blood-brain barrier (BBB) during steady-state and inflamed conditions. Within the central nervous system (CNS) the constantly changing bloodstream is strictly separated from the CNS parenchyma by the BBB. However, viruses, bacteria, parasites and auto-aggressive immune cells can penetrate the barrier and significantly contribute to CNS inflammation. The BBB can actively contribute to neuroinflammation by presentation of chemokines, expression of cell adhesion molecules and alterations of barrier properties. As such, understanding the role of the BBB under healthy and pathological conditions is essential to the development of new drugs to efficiently combat inflammatory diseases of the CNS.
Editors and Affiliations
-
Theodor Kocher Institute, University of Bern, Bern, Switzerland
Ruth Lyck, Gaby Enzmann
About the editors
Bibliographic Information
Book Title: The Blood Brain Barrier and Inflammation
Editors: Ruth Lyck, Gaby Enzmann
Series Title: Progress in Inflammation Research
DOI: https://doi.org/10.1007/978-3-319-45514-3
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer International Publishing Switzerland 2017
Hardcover ISBN: 978-3-319-45512-9Published: 10 April 2017
Softcover ISBN: 978-3-319-83308-8Published: 21 July 2018
eBook ISBN: 978-3-319-45514-3Published: 29 March 2017
Series ISSN: 1422-7746
Series E-ISSN: 2296-4525
Edition Number: 1
Number of Pages: VI, 286
Number of Illustrations: 8 b/w illustrations, 24 illustrations in colour
Topics: Immunology, Neurosciences, Membrane Biology, Infectious Diseases, Cytokines and Growth Factors