Recent Results in Cancer Research

Metabolism in Cancer

Editors: Cramer, Thorsten, Schmitt, Clemens (Eds.)

  • Covers a variety of important aspects of cancer-associated metabolism
    Presents and discusses the latest discoveries in the field
    Written by internationally respected experts

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  • ISBN 978-3-319-42118-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
Hardcover n/a
  • ISBN 978-3-319-42116-2
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About this book

This textbook presents concise chapters written by internationally respected experts on various important aspects of cancer-associated metabolism, offering a comprehensive overview of the central features of this exciting research field. The discovery that tumor cells display characteristic alterations of metabolic pathways has significantly changed our understanding of cancer: while the first description of tumor-specific changes in cellular energetics was published more than 90 years ago, the causal significance of this observation for the pathogenesis of cancer was only discovered in the post-genome era. The first 10 years of the twenty-first century were characterized by rapid advances in our grasp of the functional role of cancer-specific metabolism as well as the underlying molecular pathways. Various unanticipated interrelations between metabolic alterations and cancer-driving pathways were identified and currently await translation into diagnostic and therapeutic applications. Yet the speed, quantity, and complexity of these new discoveries make it difficult for researchers to keep up to date with the latest developments, an issue this book helps to remedy.

Table of contents (12 chapters)

  • The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells

    Brault, Charlene (et al.)

    Pages 1-22

  • Lactate—An Integrative Mirror of Cancer Metabolism

    Walenta, Stefan (et al.)

    Pages 23-37

  • Metabolic Reprogramming by the PI3K-Akt-mTOR Pathway in Cancer

    Lien, Evan C. (et al.)

    Pages 39-72

  • MYC, Metabolic Synthetic Lethality, and Cancer

    Hsieh, Annie L. (et al.)

    Pages 73-91

  • The Role of pH Regulation in Cancer Progression

    McIntyre, Alan (et al.)

    Pages 93-134

Buy this book

eBook n/a
  • ISBN 978-3-319-42118-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
Hardcover n/a
  • ISBN 978-3-319-42116-2
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Metabolism in Cancer
Editors
  • Thorsten Cramer
  • Clemens Schmitt
Series Title
Recent Results in Cancer Research
Series Volume
207
Copyright
2016
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-42118-6
DOI
10.1007/978-3-319-42118-6
Hardcover ISBN
978-3-319-42116-2
Series ISSN
0080-0015
Edition Number
1
Number of Pages
IX, 266
Number of Illustrations and Tables
6 b/w illustrations, 25 illustrations in colour
Topics