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  • © 2017

Melanoma Development

Molecular Biology, Genetics and Clinical Application

  • Presents all relevant aspects of malignant melanoma

  • Written by excellent authors

  • Unique in focusing on both, molecular mechanism and therapeutical targets

  • The 2nd Edition is updated with the newest research findings

  • Offers insight into the latest medical knowledge and therapies

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eBook USD 149.00
Price excludes VAT (USA)
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  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-viii
  2. Clinicopathologic Overview of Melanoma

    • Anja Bosserhoff, Luigi Strizzi
    Pages 1-5
  3. Melanoma Epidemiology

    • Marianne Berwick
    Pages 39-61
  4. Melanoma Genetics and Genomics

    • Allen Ho, Göran Jönsson, Hensin Tsao
    Pages 63-93
  5. Transcriptional Regulation in Melanoma

    • Satoru Yokoyama, David E. Fisher
    Pages 95-117
  6. MiRNAs in Malignant Melanoma

    • Maria Mione, Janika Liebig, Leonel Munoz, Anja Bosserhoff
    Pages 119-175
  7. Altered Signal Transduction Pathways in Melanoma

    • Yann Cheli, Eric Lau, Ze’ev A. Ronai
    Pages 177-207
  8. Proteases in Melanoma

    • Paola Zigrino, Cornelia Mauch
    Pages 209-226
  9. Cell–Cell Contacts in Melanoma and the Tumor Microenvironment

    • Silke Kuphal, Nikolas K. Haass
    Pages 227-269
  10. Senescence

    • Helen Rizos, Sebastian Haferkamp, Lyndee L. Scurr
    Pages 289-310
  11. Melanoma Stem Cells

    • Tobias F. I. Schatton, Markus H. Frank
    Pages 311-337
  12. The Birth of Malignancy: Embryogenesis and Melanoma

    • Alec Gramann, William Tyler Frantz, Craig J. Ceol
    Pages 339-355
  13. Tumor Microenvironment for Melanoma Cells

    • Lawrence W. Wu, Meenhard Herlyn, Gao Zhang
    Pages 357-368
  14. Melanoma Model Systems

    • Birgit Schittek, Miriam de Jel, Thomas Tüting
    Pages 369-398
  15. New Approaches to Signaling

    • Ryan J. Sullivan, Keith T. Flaherty
    Pages 399-425
  16. Immune Checkpoint Inhibitors in Melanoma Define a New Era in Immunotherapy Aiming for Cure

    • Alexander M. M. Eggermont, Dirk Schadendorf, Caroline Robert
    Pages 427-436
  17. Back Matter

    Pages 437-447

About this book



This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics.

Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies.

The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. 

It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.


Editors and Affiliations

  • Institute for Biochemistry, Erlangen, Germany

    Anja K. Bosserhoff

About the editor

Prof. Dr. Anja-Katrin Bosserhoff
Institute for Biochemistry


Friedrich-Alexander University Erlangen-Nürnberg
Germany
 

Bibliographic Information

  • Book Title: Melanoma Development

  • Book Subtitle: Molecular Biology, Genetics and Clinical Application

  • Editors: Anja K. Bosserhoff

  • DOI: https://doi.org/10.1007/978-3-319-41319-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing AG 2017

  • Hardcover ISBN: 978-3-319-41317-4Published: 06 February 2017

  • Softcover ISBN: 978-3-319-82322-5Published: 15 July 2018

  • eBook ISBN: 978-3-319-41319-8Published: 20 January 2017

  • Edition Number: 2

  • Number of Pages: VIII, 447

  • Number of Illustrations: 10 b/w illustrations, 26 illustrations in colour

  • Topics: Cancer Research

Buy it now

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 199.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 199.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access