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Magnetic Resonance Spectroscopy of Degenerative Brain Diseases

  • Book
  • © 2016

Overview

Editors:
  1. Gülin Öz

    1. University of Minnesota Medical School, Center Magnetic Resonance Research University of Minnesota Medical School, Minneapolis, USA

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  • A comprehensive overview of clinical and pre-clinical applications of MRS Suitable for scientists and clinicians
  • A guide to the unique information provided by biomarkers of neurodegeneration?
  • Includes supplementary material: sn.pub/extras

Part of the book series: Contemporary Clinical Neuroscience (CCNE)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xv
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  2. Imaging Neurodegeneration: What Can Magnetic Resonance Spectroscopy Contribute?

    • Gülin Öz
    Pages 1-11

  3. Methodology of MRS in Animal Models: Technical Challenges and Solutions

    • Ivan Tkáč
    Pages 13-30

  4. Methodology of Clinical MRS: Technical Challenges and Solutions

    • Bart W. J. Philips, Tom W. Scheenen
    Pages 31-54

  5. Magnetic Resonance Spectroscopy in Dementia

    • Jonathan Graff-Radford, Kejal Kantarci
    Pages 55-70

  6. Magnetic Resonance Spectroscopy in Parkinsonian Disorders

    • Ulrike Dydak, David A. Edmondson, S. Elizabeth Zauber
    Pages 71-102

  7. Magnetic Resonance Spectroscopy in Huntington’s Disease

    • Fanny Mochel, Janet M. Dubinsky, Pierre-Gilles Henry
    Pages 103-120

  8. MRS in Motor Neuron Diseases

    • Varan Govind
    Pages 121-150

  9. MR Spectroscopy in Multiple Sclerosis

    • Niamh Cawley, Olga Ciccarelli
    Pages 151-177

  10. Magnetic Resonance Spectroscopy in Ataxias

    • Pierre-Gilles Henry, H. Brent Clark, Gülin Öz
    Pages 179-200

  11. Magnetic Resonance Spectroscopy in Prion Diseases

    • Damien Galanaud
    Pages 201-207

  12. Magnetic Resonance Spectroscopy in HIV-Associated Neurocognitive Disorders: HAND

    • Eva-Maria Ratai
    Pages 209-239

  13. Magnetic Resonance Spectroscopy in Epilepsy

    • Jullie W. Pan
    Pages 241-259

  14. Back Matter

    Pages 261-268
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Keywords

About this book

The proposed book will act as a guide for scientists and clinicians to the unique information that MRS can provide. It will be a comprehensive overview of clinical and pre-clinical MRS applications and potential clinical utility of MRS biomarkers in degenerative brain diseases from leading experts in the field. MRS has proven to be a powerful complementary tool to MRI for the diagnosis and monitoring of disease progression and response to treatment because it can detect changes in cell density, cell type, and biochemical composition, not just structural changes. As the population in the developed world continues to age, neuroimaging for diagnosis, prognosis, and therapy monitoring of neurodegenerative diseases becomes increasingly important and there has been a recent surge of clinical and pre-clinical applications of MRS indicating that this technique can provide robust and non-invasive biomarkers of degeneration. ​

Editors and Affiliations

  • University of Minnesota Medical School, Center Magnetic Resonance Research University of Minnesota Medical School, Minneapolis, USA

    Gülin Öz

Bibliographic Information

  • Book Title: Magnetic Resonance Spectroscopy of Degenerative Brain Diseases

  • Editors: Gülin Öz

  • Series Title: Contemporary Clinical Neuroscience

  • DOI: https://doi.org/10.1007/978-3-319-33555-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer International Publishing Switzerland 2016

  • Hardcover ISBN: 978-3-319-33553-7Published: 09 August 2016

  • Softcover ISBN: 978-3-319-81545-9Published: 07 June 2018

  • eBook ISBN: 978-3-319-33555-1Published: 27 July 2016

  • Series ISSN: 2627-535X

  • Series E-ISSN: 2627-5341

  • Edition Number: 1

  • Number of Pages: XV, 268

  • Number of Illustrations: 23 b/w illustrations, 32 illustrations in colour

  • Topics: Neurosciences, Neurology

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