Editors:
- Covers theoretical and experimental aspects of quasispecies
- Includes the most recent developments in quasispecies research
- Provides in-depth coverage of cutting-edge research in theory and experiment ?
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 392)
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Table of contents (14 chapters)
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Front Matter
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Back Matter
About this book
This volume brings together recent developments in quasispecies theory extended to variable environments and practical applications in elucidating viral dynamics and treatment designs. In particular, the existence of an error threshold in rugged fitness landscapes has opened the way to a new antiviral strategy termed lethal mutagenesis, which is now under intensive theoretical, experimental and clinical investigation. As such the book explains how an understanding of quasispecies dynamics within infected organisms has increased our knowledge of viral disease events. From a clinical perspective, population dynamics highlights important problems for viral disease control, such as the selection of drug-resistant mutants that often accompanies treatment failures, and suggests means of increasing the effectiveness of antiviral treatments. The book is intended for students and scientists interested in basic and applied aspects of biophysics, chemistry, biology, evolution and medical virology.
Editors and Affiliations
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Campus de Cantoblanco, Centro de Biología Molecular Severo Ochoa (CSIC-UAM), Madrid, Spain
Esteban Domingo
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The Santa Fe Institute, Santa Fe, NM, USA and Institut f. Theoretische Chemie, Universität Wien, Vienna, Austria
Peter Schuster
About the editors
Bibliographic Information
Book Title: Quasispecies: From Theory to Experimental Systems
Editors: Esteban Domingo, Peter Schuster
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-319-23898-2
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2016
Hardcover ISBN: 978-3-319-23897-5Published: 29 March 2016
Softcover ISBN: 978-3-319-79548-5Published: 19 April 2018
eBook ISBN: 978-3-319-23898-2Published: 18 March 2016
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: XIV, 357
Number of Illustrations: 14 b/w illustrations, 53 illustrations in colour
Topics: Virology, Human Genetics, Immunology