Overview
- Timely book on the structure and function of unconventional pores
- Covers non-canonical channels and pores of all origins
- Written by international experts from different fields
Part of the book series: Springer Series in Biophysics (BIOPHYSICS, volume 18)
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Table of contents (15 chapters)
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Front Matter
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Bacteria and Viruses
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Front Matter
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Toxins and Antimicrobial Peptides
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Front Matter
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Keywords
About this book
This book is dedicated to the channels and pores that belong to an eclectic and ubiquitous class of unconventional - perhaps at times strange - pore-forming molecules, which nevertheless play fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores. They may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions, and for others folded polypeptides. Some are released by cells in a soluble form that has the ability to insert into biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by its virtue of focusing on a few or even a single unit, has provided invaluable insight into the mechanisms and structure-function relationships of these remarkable membrane entities. The chapters of this book highlight a representative set of these interesting investigations.
Editors and Affiliations
Bibliographic Information
Book Title: Electrophysiology of Unconventional Channels and Pores
Editors: Anne H. Delcour
Series Title: Springer Series in Biophysics
DOI: https://doi.org/10.1007/978-3-319-20149-8
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing Switzerland 2015
Hardcover ISBN: 978-3-319-20148-1Published: 03 November 2015
Softcover ISBN: 978-3-319-37235-8Published: 23 August 2016
eBook ISBN: 978-3-319-20149-8Published: 23 October 2015
Series ISSN: 0932-2353
Series E-ISSN: 1868-2561
Edition Number: 1
Number of Pages: XI, 385
Topics: Membrane Biology, Protein Structure, Biological and Medical Physics, Biophysics, Biological Techniques