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  • Book
  • © 2015

Mathematical Analysis of Complex Cellular Activity

  • First volume in a new series that covers emerging topics in the field of Applied Dynamical Systems
  • Intended for mathematicians and biologists, as well as advanced graduate students
  • Uses practical tutorials to example important connections between mathematics and physiology
  • Includes supplementary material: sn.pub/extras

Part of the book series: Frontiers in Applied Dynamical Systems: Reviews and Tutorials (FIADS, volume 1)

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Table of contents (2 chapters)

  1. Front Matter

    Pages i-xii
  2. Geometric Singular Perturbation Analysis of Bursting Oscillations in Pituitary Cells

    • Richard Bertram, Joël Tabak, Wondimu Teka, Theodore Vo, Martin Wechselberger
    Pages 1-52
  3. The Nonlinear Dynamics of Calcium

    • Vivien Kirk, James Sneyd
    Pages 53-107

About this book

This book contains two review articles on mathematical physiology that deal with closely related topics but were written and can be read independently.

The first article reviews the basic theory of calcium oscillations (common to almost all cell types), including spatio-temporal behaviors such as waves. The second article uses, and expands on, much of this basic theory to show how the interaction of cytosolic calcium oscillators with membrane ion channels can result in highly complex patterns of electrical spiking. Through these examples one can see clearly how multiple oscillatory processes interact within a cell, and how mathematical methods can be used to understand such interactions better. The two reviews provide excellent examples of how mathematics and physiology can learn from each other, and work jointly towards a better understanding of complex cellular processes.

Review 1: Richard Bertram, Joel Tabak, Wondimu Teka, Theodore Vo, Martin Wechselberger: Geometric Singular Perturbation Analysis of Bursting Oscillations in Pituitary Cells

Review 2: Vivien Kirk, James Sneyd: Nonlinear Dynamics of Calcium

Authors and Affiliations

  • Department of Mathematics, Florida State University, Tallahasse, USA

    Richard Bertram

  • Department of Mathematics and Biological, Florida State University, Tallahassee, USA

    Joel Tabak

  • Department of Mathematical Sciences, Indiana University-Purdue University Ind, Indianapolis, USA

    Wondimu Teka

  • Department of Mathematics and Statistics, Boston University, Boston, USA

    Theodore Vo

  • Department of Mathematics, University of Sydney, Sydney, Australia

    Martin Wechselberger

  • Deparment of Mathematics, The University of Auckland, Private Bag, New Zealand

    Vivien Kirk

  • Department of Mathematics, University of Auckland, Auckland, New Zealand

    James Sneyd

About the authors

Professor Richard Bertram is a Mathematics Professor at Florida State University. His current academic interests include the intersection between biology and mathematics.

Professor James Sneyd is a Professor in Applied Mathematics at The University of Auckland and his current research interests include mathematical physiology and nonlinear dynamical systems.

Bibliographic Information

Buy it now

Buying options

eBook USD 44.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 59.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access