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Comparative Effectiveness in Surgical Oncology

Key Questions and How to Answer Them

  • Book
  • © 2015

Overview

Editors:
  1. Karl Y. Bilimoria

    1. Department of Surgery, Northwestern University, Chicago, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Christina A. Minami

    1. Northwestern University, Chicago, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. David M. Mahvi

    1. Department of Surgery, Northwestern University, Chicago, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Sets out the current critical questions regarding the treatment of each major malignancy
  • Proposes approaches to gain answers to these questions
  • Explains the concept of comparative effectiveness research?
  • Includes supplementary material: sn.pub/extras

Part of the book series: Cancer Treatment and Research (CTAR, volume 164)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Approaches to Answering Critical CER Questions

    • Christine V. Kinnier, Jeanette W. Chung, Karl Y. Bilimoria
    Pages 1-14

  3. Leveraging Comparative Effectiveness Research to Improve the Quality of Multidisciplinary Care for Breast Cancer Patients

    • Lane L. Frasier, Caprice C. Greenberg, Heather B. Neuman
    Pages 15-30

  4. Comparative Effectiveness in Melanoma

    • Maria C. Russel, Keith A. Delman
    Pages 31-49

  5. Comparative Effectiveness Research for Sarcoma

    • Nabil Wasif
    Pages 51-65

  6. Comparative Effectiveness in Thyroid Cancer: Key Questions and How to Answer Them

    • Elliot A. Asare, Tracy S. Wang
    Pages 67-87

  7. Comparative Effectiveness in Head and Neck Malignancies

    • Carol M. Lewis, Katherine A. Hutcheson, Michael E. Kupferman
    Pages 89-99

  8. Comparative Effectiveness Issues in Lung Cancer

    • Thomas K. Varghese
    Pages 101-119

  9. Comparative Effectiveness in Esophagogastric Cancer

    • Lawrence M. Knab, Jim Belotte, Hidayatullah G. Munshi, David J. Bentrem
    Pages 121-142

  10. Comparative Effectiveness in Colon and Rectal Cancer

    • Christine C. Jensen, Robert D. Madoff
    Pages 143-163

  11. Research Gaps in Pancreatic Cancer Research and Comparative Effectiveness Research Methodologies

    • Haejin In, Mitchell C. Posner
    Pages 165-194

  12. Comparative Effectiveness in Hepatic Malignancies

    • Andrew J. Page, David Cosgrove, Timothy M. Pawlik
    Pages 195-219

  13. Comparative Effectiveness Research in Urologic Cancers

    • Seth A. Strope
    Pages 221-235

  14. Comparative Effectiveness Research in Gynecologic Oncology

    • Sonali Patankar, Ana I. Tergas, Jason D. Wright
    Pages 237-259
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Keywords

About this book

Despite tremendous recent advances in the treatment of most malignancies, there remain several critical questions for each cancer. This particularly true for the surgical management of solid-organ malignancies. Comparative effectiveness is a relatively new term which encompasses the age-old concepts of how best to treat cancer patients. Comparative effectiveness is defined as the direct comparison of healthcare interventions to determine which work best for which patients when considering the benefits and risks. The Institute of Medicine has defined comparative effectiveness research(CER) as the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care. CER is certainly best done with well-conducted randomized controlled trials. Unfortunately, clinical trials are not always feasible owing to the impracticality of conducting the trial, the considerablecost, and the time required to complete the trial. These challenges are even more pronounced with respect to surgical treatment. Thus alternative approaches may need to be considered in order to address pressing questions in the care of the oncology patient. These approaches may include well-conducted retrospective cohort studies from cancer registries and other data sources, decision and cost-effectiveness analyses, and other novel methodologies. This book lays out the current critical questions for each major malignancy and proposes approaches to gain answers to these pressing questions.

Reviews

“The book applies the concepts of Comparative Effectiveness Research (CER) to a long list of malignancies and asks how the key questions associated with each have been addressed or could be addressed using this methodology. … The audience is surgical oncologists, and within that specialized field, the book will appeal primarily to researchers and academic surgeons. … This is a highly specialized monograph that will appeal to researchers in the surgical oncology and their trainees seeking ideas for research.” (Carol Scott-Conner, Doody’s Book Reviews, April, 2016)

Editors and Affiliations

  • Department of Surgery, Northwestern University, Chicago, USA

    Karl Y. Bilimoria, David M. Mahvi

  • Northwestern University, Chicago, USA

    Christina A. Minami

Bibliographic Information

  • Book Title: Comparative Effectiveness in Surgical Oncology

  • Book Subtitle: Key Questions and How to Answer Them

  • Editors: Karl Y. Bilimoria, Christina A. Minami, David M. Mahvi

  • Series Title: Cancer Treatment and Research

  • DOI: https://doi.org/10.1007/978-3-319-12553-4

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-12552-7Published: 19 March 2015

  • Softcover ISBN: 978-3-319-37868-8Published: 06 October 2016

  • eBook ISBN: 978-3-319-12553-4Published: 12 February 2015

  • Series ISSN: 0927-3042

  • Series E-ISSN: 2509-8497

  • Edition Number: 1

  • Number of Pages: XV, 259

  • Number of Illustrations: 8 b/w illustrations, 6 illustrations in colour

  • Topics: Oncology, Surgery

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