Informing Clinical Practice in Nephrology

The Role of RCTs

Editors: El Kossi, Mohsen, Khwaja, Arif, El Nahas, Meguid (Eds.)

  • Only book available that addresses the role of RCTs in informing clinical practice in Nephrology
  • Provides a reference for key clinical trials in the different areas of renal medicine
  • Will help the practicing physician close the gap between the clinical guidelines and day-to-day clinical decision-making for individual patients​​
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Buy this book

eBook $79.99
price for USA (gross)
  • ISBN 978-3-319-10292-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $109.00
price for USA
  • ISBN 978-3-319-10291-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $109.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 18, 2016
  • ISBN 978-3-319-34820-9
  • Free shipping for individuals worldwide
About this book

Historically, clinical decisions in renal medicine have been challenged by the scarce availability of robust supportive evidence. Not only are the number of randomized controlled trials (RCTs) in Nephrology the third lowest amongst the medical specialties but in many instances the trials themselves are of poor quality. In addition, practice has been further influenced by extrapolation from the outcomes of general population clinical trials which exclude renal patients. The difference between the ideal trial participant and real complex cases encountered in daily practice is well recognized and further compounded in renal patients with complex pathophysiology - this ultimately makes decision making in this subset of patients a real challenge. Recently, there has been a growing interest in conducting well designed RCTs in different areas of renal medicine. However, though clinical guidelines are helpful in providing the clinicians with a frame of best available evidence for a clinical condition, it denies the unique nature of each individual patient.

This book offers a thorough and critical appraisal and evaluation of the key published clinical trials that have shaped current practice in nephrology, dialysis and transplantation. It will help the practicing physician close the gap between the inflexible and generalized nature of clinical guidelines and the day-to-day clinical decision-making for individual patients. It will provide the clinician with the tools required to investigate and extract the appropriate guidance to apply to individual cases in daily practice. Moreover, it will help improve the ability of junior colleagues to appraise available evidence in a systematic way when there is lack of local guidelines or when the guidelines are difficult to apply due to logistic constraints or barriers. Lastly, this book will serve as a reference for key clinical trials in different areas of renal medicine together with literature and authors views of these trials and their impact on changing practice.​ 

Reviews

“This book provides an interesting look at several important trials in the field of nephrology. … This book will be very useful for students, residents, and fellows learning to critically analyze published trials, but it also will appeal to providers in the field who encounter these clinical situations. … This will be a great asset for those involved in the care of patients with kidney disease.” (Jon Webb, Doody’s Book Reviews, April, 2016)


Table of contents (13 chapters)

  • Autosomal Dominant Polycystic Kidney Disease (ADPKD) Clinical Trials: A Critical Appraisal

    Swami, Vimarsha G. (et al.)

    Pages 1-15

  • Lupus Nephritis Clinical Trials: A Critical Appraisal

    Glassock, Richard J.

    Pages 17-31

  • ANCA-Associated Glomerulonephritis Clinical Trials: A Critical Appraisal

    Mahdi, Khalid (et al.)

    Pages 33-46

  • Acute Kidney Injury (AKI) Clinical Trials: A Critical Appraisal

    Zeng, Yangmin (et al.)

    Pages 47-69

  • Chronic Kidney Disease (CKD) Clinical Trials: A Critical Appraisal

    El Nahas, Meguid

    Pages 71-91

Buy this book

eBook $79.99
price for USA (gross)
  • ISBN 978-3-319-10292-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $109.00
price for USA
  • ISBN 978-3-319-10291-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $109.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 18, 2016
  • ISBN 978-3-319-34820-9
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Informing Clinical Practice in Nephrology
Book Subtitle
The Role of RCTs
Editors
  • Mohsen El Kossi
  • Arif Khwaja
  • Meguid El Nahas
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-10292-4
DOI
10.1007/978-3-319-10292-4
Hardcover ISBN
978-3-319-10291-7
Softcover ISBN
978-3-319-34820-9
Edition Number
1
Number of Pages
XII, 243
Number of Illustrations and Tables
1 b/w illustrations
Topics