Protein Folding and Structure

Intrinsically Disordered Proteins

Authors: Uversky, Vladimir N.

  • Discusses applications of IDPs and IDPRs as potential drug targets
  • Includes an introduction to the concept of protein intrinsic disorder
  • Provides an overview of current literature in the field
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eBook $39.99
price for USA (gross)
  • ISBN 978-3-319-08921-8
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  • Immediate eBook download after purchase
Softcover $54.99
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  • ISBN 978-3-319-08920-1
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About this book

In this brief, Vladimir Uversky discusses the paradigm-shifting phenomenon of intrinsically disordered proteins (IDPs) and hybrid proteins containing ordered domains and functional IDP regions (IDPRs). Beginning with an introduction to the concept of protein intrinsic disorder, Uversky then goes on to describe the peculiar amino acid sequences of IDPs, their structural heterogeneity, typical functions and disorder-based binding modes. In the final sections, Uversky discusses IDPs in human diseases and as potential drug targets. This volume provides a snapshot to researchers entering the field as well as providing a current overview for more experienced scientists in related areas.

About the authors

Vladimir Uversky obtained his Ph.D. in biophysics from Moscow Institute of Physics and Technology (1991) and D.Sc. in biophysics from Institute of Experimental and Theoretical Biophysics, Russian Academy of Sciences (1998). He spent early career working on protein folding at Institute of Protein Research and the Institute for Biological Instrumentation (Russian Academy of Sciences). In 1998, he moved to the University of California Santa Cruz to work on protein folding, misfolding and protein intrinsic disorder. In 2004, he moved to the Center for Computational Biology and Bioinformatics at the Indiana University Purdue University Indianapolis to work on the intrinsically disordered proteins. Since 2010, he is with the Department of Molecular Biology at the University of South Florida.

Table of contents (1 chapters)

  • Intrinsically Disordered Proteins

    Uversky, Vladimir N.

    Pages 1-51

Buy this book

eBook $39.99
price for USA (gross)
  • ISBN 978-3-319-08921-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $54.99
price for USA
  • ISBN 978-3-319-08920-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Intrinsically Disordered Proteins
Authors
Series Title
Protein Folding and Structure
Copyright
2014
Publisher
Springer International Publishing
Copyright Holder
The Author(s)
eBook ISBN
978-3-319-08921-8
DOI
10.1007/978-3-319-08921-8
Softcover ISBN
978-3-319-08920-1
Series ISSN
2199-3157
Edition Number
1
Number of Pages
XV, 61
Number of Illustrations and Tables
3 b/w illustrations, 10 illustrations in colour
Topics