Current Topics in Microbiology and Immunology

Fc Receptors

Editors: Daëron, Marc, Nimmerjahn, Falk (Eds.)

  • Written by leading experts in the field
  • Provides a comprehensive and up to date overview of Fc receptors
  • Covers aspects of Fc receptor-targeted therapies for the treatment of inflammation, cancer and other diseases
see more benefits

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-319-07911-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-319-07910-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 7, 2016
  • ISBN 978-3-319-37909-8
  • Free shipping for individuals worldwide
About this book

This volume provides a state-of-the-art update on Fc Receptors (FcRs). It is divided into five parts. Part I, Old and New FcRs, deals with the long-sought-after FcµR and the recently discovered FCRL family and TRIM21. Part II, FcR Signaling, presents a computational model of FcεRI signaling, novel calcium channels, and the lipid phosphatase SHIP1. Part III, FcR Biology, addresses major physiological functions of FcRs, their glycosylation, how they induce and regulate both adaptive immune responses and inflammation, especially in vivo, FcR humanized mice, and the multifaceted properties of FcRn. Part IV, FcRs and Disease, discusses FcR polymorphism, FcRs in rheumatoid arthritis and whether their FcRs make macaques good models for studying HIV infection. In Part V, FcRs and Therapeutic Antibodies, the roles of various FcRs, including FcγRIIB and FcαRI, in the immunotherapy of cancer and autoimmune diseases using monoclonal antibodies and IVIg are highlighted. All 18 chapters were written by respected experts in their fields, offering an invaluable reference source for scientists and clinicians interested in FcRs and how to better master antibodies for therapeutic purposes.

Table of contents (18 chapters)

  • The Old but New IgM Fc Receptor (FcμR)

    Kubagawa, Hiromi (et al.)

    Pages 3-28

  • Emerging Roles for the FCRL Family Members in Lymphocyte Biology and Disease

    Li, F. J. (et al.)

    Pages 29-50

  • Intracellular Antibody Immunity and the Cytosolic Fc Receptor TRIM21

    James, Leo C.

    Pages 51-66

  • Computational Modeling of the Main Signaling Pathways Involved in Mast Cell Activation

    Niarakis, Anna (et al.)

    Pages 69-93

  • Calcium Channels in Fc Receptor Signaling

    Attout, Tarik (et al.)

    Pages 95-110

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-319-07911-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-319-07910-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 7, 2016
  • ISBN 978-3-319-37909-8
  • Free shipping for individuals worldwide
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Fc Receptors
Editors
  • Marc Daëron
  • Falk Nimmerjahn
Series Title
Current Topics in Microbiology and Immunology
Series Volume
382
Copyright
2014
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-07911-0
DOI
10.1007/978-3-319-07911-0
Hardcover ISBN
978-3-319-07910-3
Softcover ISBN
978-3-319-37909-8
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XV, 424
Number of Illustrations and Tables
11 b/w illustrations, 44 illustrations in colour
Topics