Current Topics in Microbiology and Immunology

Transcriptional Control of Lineage Differentiation in Immune Cells

Editors: Ellmeier, Wilfried, Taniuchi, Ichiro (Eds.)

  • Illustrates key transcriptional control mechanisms in immune cells
  • Provides insight into the transcriptional regulatory circuits underlying innate and adaptive immunity
  • Richly illustrated
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eBook $159.00
price for USA (gross)
  • ISBN 978-3-319-07395-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-3-319-07394-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 7, 2016
  • ISBN 978-3-319-37651-6
  • Free shipping for individuals worldwide
About this book

Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during the differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade.

About the authors

Wilfried Ellmeier, PhD., is Professor of Immunology at the Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology Medical University of Vienna, Austria. Taniuchi Ichiro, M.D. PhD. Professor is Group Director of the Laboratory for Transcriptional Regulation RIKEN Research Center for Allergy and Immunology (RCAI), Japan.

Table of contents (10 chapters)

  • Genetic and Epigenetic Control of Early Lymphocyte Development

    Ikawa, Tomokatsu

    Pages 1-20

  • The Role of BTB-Zinc Finger Transcription Factors During T Cell Development and in the Regulation of T Cell-mediated Immunity

    Ellmeier, Wilfried (et al.)

    Pages 21-49

  • Transcriptional Control of the Development and Function of Vα14i NKT Cells

    Engel, Isaac (et al.)

    Pages 51-81

  • Transcriptional Control of Regulatory T cells

    Delacher, Michael (et al.)

    Pages 83-124

  • Transcriptional Regulatory Networks for CD4 T Cell Differentiation

    Christie, Darah (et al.)

    Pages 125-172

Buy this book

eBook $159.00
price for USA (gross)
  • ISBN 978-3-319-07395-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $209.00
price for USA
  • ISBN 978-3-319-07394-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $209.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: October 7, 2016
  • ISBN 978-3-319-37651-6
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Transcriptional Control of Lineage Differentiation in Immune Cells
Editors
  • Wilfried Ellmeier
  • Ichiro Taniuchi
Series Title
Current Topics in Microbiology and Immunology
Series Volume
381
Copyright
2014
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-07395-8
DOI
10.1007/978-3-319-07395-8
Hardcover ISBN
978-3-319-07394-1
Softcover ISBN
978-3-319-37651-6
Series ISSN
0070-217X
Edition Number
1
Number of Pages
VIII, 331
Topics