Advances in Experimental Medicine and Biology

Advancements of Mass Spectrometry in Biomedical Research

Editors: Woods, Alisa G., Darie, Costel C. (Eds.)

  • Covers therapeutic fields utilizing mass spectrometry and proteomic discovery, including the newest field, psychiatry
  • Discusses the most recent proteomic methodology as well as innovative approaches to protein separation that increase the power of this technique
  • Describes how researchers unfamiliar with mass spectrometry may partner with proteomic scientists most optimally to enhance their own work​
see more benefits

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-3-319-06068-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-3-319-06067-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 10, 2016
  • ISBN 978-3-319-37892-3
  • Free shipping for individuals worldwide
About this book

This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field.

Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.

About the authors

 Dr. Costel C. Darie started his biomedical career as a nurse at the Murgeni Hospital, Romania. He received his BS and MS in biochemistry at the Alexandru Ioan Cuza University from Iasi, Romania, and performed research under Dr. Vlad Artenie. He continued his Ph.D. studies with Dr. Wolfgang Haehnel at the Albert-Ludwigs Universitaet, Freiburg, Germany, after which he worked in the labs of Drs. Paul M. Wassarman & Micsunica Platica (Mount Sinai School of Medicine) and Thomas A. Neubert (New York University Medical Center). He currently is an Assistant Professor of Chemistry and Biomolecular Science at Clarkson University, where he is the lead of the Biochemistry and Proteomics Group.

Dr. Alisa Woods received her BS in psychology from the State University of New York (SUNY) at Plattsburgh and her PhD in biology from the University of California, Irvine, with Dr. Christine Gall. She continued with post-doctoral training at the University of Freiburg, Germany, with Dr. Michael Frotscher and completed a Master's degree in Mental Health Counseling at the University of Massachusetts, Boston. She is currently a Research Assistant Professor of Chemistry and Biomolecular Science at Clarkson University, where she works in the Laboratory for Biochemistry and Proteomics. She is also a counselor and neuropsychology researcher at the Neuropsychology Clinic at SUNY Plattsburgh.

Reviews

“Intended for intermediate and experienced readers, this is recommended reading and a must-have laboratory resource for those already involved in proteomics research. Advancements of mass spectrometry in biomedical research describes essential principles of MS and proteomics. It also offers updated information on popular proteomics-based MS applications and newly developed techniques. … It is recommended as both a textbook and a great laboratory benchtop reference.” (Mitsutoshi Setou and Ikuko Yao, Analytical and Bioanalytical Chemistry, Vol. 407, 2015)


Table of contents (29 chapters)

  • Mass Spectrometry for Proteomics-Based Investigation

    Woods, Alisa G. (et al.)

    Pages 1-32

  • MALDI Profiling and Applications in Medicine

    Dudley, Ed

    Pages 33-58

  • Simplifying the Proteome: Analytical Strategies for Improving Peak Capacity

    Gethings, Lee A. (et al.)

    Pages 59-77

  • Quantitative Shotgun Proteomics with Data-Independent Acquisition and Traveling Wave Ion Mobility Spectrometry: A Versatile Tool in the Life Sciences

    Brown, Lewis M.

    Pages 79-91

  • Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) for Quantitative Proteomics

    Hoedt, Esthelle (et al.)

    Pages 93-106

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-3-319-06068-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-3-319-06067-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $179.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • Due: November 10, 2016
  • ISBN 978-3-319-37892-3
  • Free shipping for individuals worldwide
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Advancements of Mass Spectrometry in Biomedical Research
Editors
  • Alisa G. Woods
  • Costel C. Darie
Series Title
Advances in Experimental Medicine and Biology
Series Volume
806
Copyright
2014
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-06068-2
DOI
10.1007/978-3-319-06068-2
Hardcover ISBN
978-3-319-06067-5
Softcover ISBN
978-3-319-37892-3
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XVI, 600
Number of Illustrations and Tables
47 b/w illustrations, 126 illustrations in colour
Topics