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The Hologenome Concept: Human, Animal and Plant Microbiota

Authors: Rosenberg, Eugene, Zilber-Rosenberg, Ilana

  • Up-to-date critical review of research on the functions of microbiota in plants, animals and humans
  • Paradigm change in biology: Consideration of the holobiont as an authentic, biological entity and a level of selection in evolution
  • A novel discussion of variation and evolution emphasizing cooperation between microbes and their hosts from the formation of the first eukaryote to the present
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eBook $149.00
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  • ISBN 978-3-319-04241-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
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  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-319-04240-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • ISBN 978-3-319-34938-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days. October 14, 2016
About this book

Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution.

All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.

Table of contents (11 chapters)

  • Introduction: Symbioses and the Hologenome Concept

    Rosenberg, Eugene (et al.)

    Pages 1-8

  • Origin of Prokaryotes and Eukaryotes

    Rosenberg, Eugene (et al.)

    Pages 9-22

  • Abundance and Diversity of Microbiota

    Rosenberg, Eugene (et al.)

    Pages 23-40

  • Microbiotas are Transmitted Between Holobiont Generations

    Rosenberg, Eugene (et al.)

    Pages 41-54

  • Microbiotas are Part of Holobiont Fitness

    Rosenberg, Eugene (et al.)

    Pages 55-80

Buy this book

eBook $149.00
price for USA
  • ISBN 978-3-319-04241-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-319-04240-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • Customers within the U.S. and Canada please contact Customer Service at 1-800-777-4643, Latin America please contact us at +1-212-460-1500 (Weekdays 8:30am – 5:30pm ET) to place your order.
  • ISBN 978-3-319-34938-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days. October 14, 2016
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Bibliographic Information

Bibliographic Information
Book Title
The Hologenome Concept: Human, Animal and Plant Microbiota
Authors
Copyright
2013
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-04241-1
DOI
10.1007/978-3-319-04241-1
Hardcover ISBN
978-3-319-04240-4
Softcover ISBN
978-3-319-34938-1
Edition Number
1
Number of Pages
XIII, 178
Topics