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Mechanisms of Atrial Arrhythmias

Insights from the Development of a Biophysically Detailed Model of the Human Atria

  • Book
  • © 2014

Overview

  • Nominated as an outstanding Ph.D. thesis by the University of Manchester, UK
  • Elucidates the mechanisms underlying atrial fibrillation
  • May assist in the prevention and treatment of atrial fibrillation
  • Provides detailed, multi-scale model of the heterogeneous human atria and torso
  • Provides models of anatomically accurate and electrophysiologically detailed pacemaker structures
  • Includes supplementary material: sn.pub/extras

Part of the book series: Springer Theses (Springer Theses)

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Table of contents (9 chapters)

  1. Single Cell Modelling of the Human Atria

  2. 3-D Modelling of the Human Atria

Keywords

About this book

This thesis describes the development of biophysically detailed computer models of the human atria and torso to study the underlying mechanisms of cardiac diseases, some of the most common causes of morbidity and mortality. This is a cross-disciplinary project, involving fundamentals of cardiac electrophysiology, physics of excitable media, applied mathematics and high performance scientific computing and visualisation. The author uses computer models to provide insights into the underlying mechanisms of the genesis of atrial fibrillation and develops novel techniques for the monitoring of atrial tachycardia.

Authors and Affiliations

  • School of Physics and Astronomy, University of Manchester, Manchester, United Kingdom

    Michael A. Colman

Bibliographic Information

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