Springer Theses

Organotrifluoroborate Preparation, Coupling and Hydrolysis

Authors: Lennox, Alastair J. J.

  • Nominated as an outstanding Ph.D. thesis by the University of Bristol, UK
  • Includes an extensive review on organotrifluoroborate salts
  • Demonstrates a new, simple and etch-free preparation method for organotrifluoroborate salts
  • Detailed mechanistic studies reveal the reactivity of organotrifluoroborate salts in Suzuki-Miyaura coupling reactions
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eBook $99.00
price for USA (gross)
  • ISBN 978-3-319-01134-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA
  • ISBN 978-3-319-01133-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $129.00
price for USA
  • ISBN 978-3-319-37734-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Alistair Lennox's thesis reports on the reactivity of organotrifluoroborates, which are becoming increasingly important reagents in synthesis. The thesis is divided into three sections. The first section describes a method for preparing organotrifluoroborates. The second section reports on a mechanistic investigation into the main application of RBF3K reagents as coupling partners in Suzuki-Miyaura coupling, phenomena identified as arising from organotrifluoroborate hydrolysis and fluoride release. The final section reports on a detailed investigation into the hydrolysis mechanism, a prerequisite for their Suzuki-Miyaura coupling, and how it may be predicted and controlled. This research has uncovered many interesting and useful details and shows how problems associated with Suzuki-Miyaura coupling can best be addressed. There has already been wide industrial uptake of the new procedures and insights. The broad nature and clear and succinct style will make the thesis a valuable resource for anyone working in synthesis, organometallic chemistry, or in homogeneous catalysis.

About the authors

Dr. Lennox grew up in York, received his undergraduate degree from the University of Manchester and his PhD from the University of Bristol. His interests lie in organic reaction mechanisms, of which his PhD thesis was focussed and the subject of a book he is currently co-writing.

Table of contents (6 chapters)

  • General Introduction

    Lennox, Alastair J. J.

    Pages 1-9

  • Organotrifluoroborate Preparation

    Lennox, Alastair J. J.

    Pages 11-36

  • Organotrifluoroborate Coupling

    Lennox, Alastair J. J.

    Pages 37-80

  • Organotrifluoroborate Hydrolysis

    Lennox, Alastair J. J.

    Pages 81-131

  • Conclusions and Future work

    Lennox, Alastair J. J.

    Pages 133-146

Buy this book

eBook $99.00
price for USA (gross)
  • ISBN 978-3-319-01134-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $129.00
price for USA
  • ISBN 978-3-319-01133-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $129.00
price for USA
  • ISBN 978-3-319-37734-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Organotrifluoroborate Preparation, Coupling and Hydrolysis
Authors
Series Title
Springer Theses
Copyright
2013
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-01134-9
DOI
10.1007/978-3-319-01134-9
Hardcover ISBN
978-3-319-01133-2
Softcover ISBN
978-3-319-37734-6
Series ISSN
2190-5053
Edition Number
1
Number of Pages
XV, 223
Number of Illustrations and Tables
212 b/w illustrations, 96 illustrations in colour
Topics