Milestones in Drug Therapy

Tamoxifen

Pioneering Medicine in Breast Cancer

Authors: Maximov, Philipp Y., McDaniel, Russell E., Jordan, V. Craig

  • The story of Tamoxifen written first-hand by the "father of tamoxifen"
  • A personal journey through four decades of discovery that changed women’s health
  • Including an interview with the pioneer of the therapy
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eBook $149.00
price for USA (gross)
  • ISBN 978-3-0348-0664-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-0348-0663-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-0348-0783-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years.

This monograph, written by V. Craig Jordan - known as the “father of tamoxifen” - and his Tamoxifen Team at the Georgetown University Washington DC, illustrates the journey of this milestone in medicine. It includes a personal interview with V. Craig Jordan about his four decades of discovery in breast cancer research and treatment. V. Craig Jordan was there for the birth of tamoxifen as he is credited for reinventing a “failed morning after contraceptive” to become the “gold standard” for the treatment of breast cancer. He contributed to every aspect of tamoxifen application in therapeutics and all aspects of tamoxifen’s pharmacology. He discovered the selective estrogen receptor modulators (SERMs) and explored the new biology of estrogen-induced apoptosis.

Reviews

From the book reviews:

“This is a book that had to be written. … This book should be available in every oncology department. The story will interest clinicians and laboratory scientists alike. It has both historical value and value as a guide that will illuminate the path to successful involvement in cancer research for younger cancer researchers.” (R. M. Lowenthal, Inflammopharmacology, Vol. 22 (3), June, 2014)

“This is a very well-written, readable book for anyone who has an interest in the prevention and treatment of breast cancer, ranging from those involved in drug discovery to those who are treating and taking care of patients with breast cancer. Likewise, anyone who has a loved one who has, or is at high risk for, breast cancer will find this an excellent read. … It is a well-done and interesting read.” (Thomas L. Pazdernik, Doody’s Book Reviews, November, 2013)

Table of contents (10 chapters)

  • Discovery and Pharmacology of Nonsteroidal Estrogens and Antiestrogens

    Maximov, Philipp Y. (et al.)

    Pages 1-30

  • Tamoxifen Goes Forward Alone

    Maximov, Philipp Y. (et al.)

    Pages 31-46

  • Metabolites of Tamoxifen as the Basis of Drug Development

    Maximov, Philipp Y. (et al.)

    Pages 47-67

  • Adjuvant Therapy: The Breakthrough

    Maximov, Philipp Y. (et al.)

    Pages 69-84

  • The Wisconsin Story in the 1980s: Discovery of Target Site-Specific Estrogen Action

    Maximov, Philipp Y. (et al.)

    Pages 85-99

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-3-0348-0664-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-3-0348-0663-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $189.00
price for USA
  • ISBN 978-3-0348-0783-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Tamoxifen
Book Subtitle
Pioneering Medicine in Breast Cancer
Authors
Series Title
Milestones in Drug Therapy
Copyright
2013
Publisher
Springer Basel
Copyright Holder
Springer Basel
eBook ISBN
978-3-0348-0664-0
DOI
10.1007/978-3-0348-0664-0
Hardcover ISBN
978-3-0348-0663-3
Softcover ISBN
978-3-0348-0783-8
Series ISSN
2296-6056
Edition Number
1
Number of Pages
XXII, 202
Topics