Progress in Inflammation Research

Proteases and Their Receptors in Inflammation

Editors: Vergnolle, Nathalie, Chignard, Michel (Eds.)

  • Presents the most advanced knowledge in the field.
  • Written by renowned experts.
  • Richly illustrated.
see more benefits

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-3-0348-0157-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-3-0348-0156-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-3-0348-0342-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
About this book

Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest.  In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response.

This volume presents all advances in our knowledge of the role proteases and their inhibitors play in various diseases associated with inflammatory response. Mechanisms involved in protease signaling to cells are presented, and the different types of proteases that are present at inflammatory sites and their effects on the course of inflammation are discussed. Finally, the evidence for considering proteases and their receptors as potential molecular targets for therapeutic interventions in the treatment of inflammatory diseases is discussed in the context of specific organ inflammatory pathologies (the lung, gastrointestinal tract, skin, joints, etc.).

Table of contents (13 chapters)

  • Proteolytic Enzymes and Cell Signaling: Pharmacological Lessons

    Hollenberg, Morley D. (et al.)

    Pages 1-25

  • Serine and Cysteine Proteases and Their Inhibitors as Antimicrobial Agents and Immune Modulators

    Manoury, Bénédicte (et al.)

    Pages 27-50

  • Kallikrein Protease Involvement in Skin Pathologies Supports a New View of the Origin of Inflamed Itchy Skin

    Eissa, Azza (et al.)

    Pages 51-71

  • Proteases from Inflammatory Cells: Regulation of Inflammatory Response

    Pederzoli-Ribeil, Magali (et al.)

    Pages 73-100

  • Matrix Metalloproteinase Inhibitors as New Anti-inflammatory Drugs

    Lagente, Vincent (et al.)

    Pages 101-122

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-3-0348-0157-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-3-0348-0156-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-3-0348-0342-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Proteases and Their Receptors in Inflammation
Editors
  • Nathalie Vergnolle
  • Michel Chignard
Series Title
Progress in Inflammation Research
Copyright
2011
Publisher
Springer Basel
Copyright Holder
Springer Basel AG
eBook ISBN
978-3-0348-0157-7
DOI
10.1007/978-3-0348-0157-7
Hardcover ISBN
978-3-0348-0156-0
Softcover ISBN
978-3-0348-0342-7
Edition Number
1
Number of Pages
XIV, 310
Topics