Milestones in Drug Therapy

Treatment and Prevention of Malaria

Antimalarial Drug Chemistry, Action and Use

Editors: Staines, Henry M., Krishna, Sanjeev (Eds.)

  • Gives a comprehensive account of the recent advances in anti-malaria drugs
  • Chapters contributed by expert authors
  • Describes new ideas and directions for study
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eBook $199.00
price for USA (gross)
  • ISBN 978-3-0346-0480-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-3-0346-0479-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-3-0348-0808-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions.  

Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.

Reviews

From the reviews:

“Staines and Krishna successfully captures the essence of what we know about antimalarials at the beginning of the second decade of the 21st century. … the book is a welcome and highly valuable documentation on where we stand and offers valuable food for thought in the search for the way forward.” (Martin P. Grobusch, Trends in Parasitology, September, 2012)


Table of contents (15 chapters)

  • Antimalarial Drugs and the Control and Elimination of Malaria

    Barnes, Karen I.

    Pages 1-17

  • 4-Aminoquinolines: Chloroquine, Amodiaquine and Next-Generation Analogues

    O’Neill, Paul M. (et al.)

    Pages 19-44

  • Cinchona Alkaloids: Quinine and Quinidine

    Sullivan, David J.

    Pages 45-68

  • 8-Aminoquinolines: Primaquine and Tafenoquine

    Waters, Norman C. (et al.)

    Pages 69-94

  • Other 4-Methanolquinolines, Amyl Alcohols and Phentathrenes: Mefloquine, Lumefantrine and Halofantrine

    Nosten, Francois (et al.)

    Pages 95-111

Buy this book

eBook $199.00
price for USA (gross)
  • ISBN 978-3-0346-0480-2
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $259.00
price for USA
  • ISBN 978-3-0346-0479-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $259.00
price for USA
  • ISBN 978-3-0348-0808-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Treatment and Prevention of Malaria
Book Subtitle
Antimalarial Drug Chemistry, Action and Use
Editors
  • Henry M. Staines
  • Sanjeev Krishna
Series Title
Milestones in Drug Therapy
Copyright
2012
Publisher
Springer Basel
Copyright Holder
Springer Basel AG
eBook ISBN
978-3-0346-0480-2
DOI
10.1007/978-3-0346-0480-2
Hardcover ISBN
978-3-0346-0479-6
Softcover ISBN
978-3-0348-0808-8
Series ISSN
2296-6056
Edition Number
1
Number of Pages
X, 318
Topics