Birkhäuser Advances in Infectious Diseases

Replicating Vaccines

A New Generation

Editors: Dormitzer, Philip, Mandl, Christian W., Rappuoli, Rino (Eds.)

  • Highlights new approaches to the generation of live vaccines
  • Includes discussion of risks and safety aspects
  • Covers a variety of infectious organisms
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eBook $229.00
price for USA (gross)
  • ISBN 978-3-0346-0277-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-3-0346-0276-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-3-0348-0316-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Technological advances, together with a better understanding of the molecular biology of infectious microorganisms, are creating exciting possibilities for a new generation of replicating vaccines. Historically, live vaccines have been either directly derived from a natural source or attenuated by empirical approaches using serial passages and host cell adaptation. Currently, we are witnessing a quantum leap in our technological capabilities to specifically modify the genetic make-up of viruses and bacteria, making it possible to generate improved live vaccines and to develop completely new types of replicating vaccines, such as vectored vaccines, single-round infectious vaccines and replicon vaccines. This book highlights some of the most exciting recent developments towards a new generation of replicating vaccines.

Reviews

From the reviews:

“This book introduces the current thinking on rational attenuation and this important theme runs through the book, tying the chapters together very nicely. … Given the renaissance in vaccinology this is a timely volume which … makes judicious use of selected examples to highlight key aspects of this burgeoning field. This book is both a useful primer for students and a thought-provoking read for researchers in this field.” (Paul Duprex, Microbiology Today, November, 2011)

Table of contents (16 chapters)

  • Live Vaccines and Their Role in Modern Vaccinology

    Dougan, Gordon (et al.)

    Pages 3-14

  • Live Attenuated Vaccines: Influenza, Rotavirus and Varicella Zoster Virus

    Greenberg, Harry B. (et al.)

    Pages 15-46

  • Classical Live Viral Vaccines

    , Thomas

    Pages 47-69

  • Recombinant Live Vaccines to Protect Against the Severe Acute Respiratory Syndrome Coronavirus

    Enjuanes, Luis (et al.)

    Pages 73-97

  • Live-Attenuated Shigella Vaccines. Is Encouraging Good Enough?

    Germani, Yves (et al.)

    Pages 99-117

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-3-0346-0277-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-3-0346-0276-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-3-0348-0316-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Replicating Vaccines
Book Subtitle
A New Generation
Editors
  • Philip Dormitzer
  • Christian W. Mandl
  • Rino Rappuoli
Series Title
Birkhäuser Advances in Infectious Diseases
Copyright
2011
Publisher
Springer Basel
Copyright Holder
Springer Basel AG
eBook ISBN
978-3-0346-0277-8
DOI
10.1007/978-3-0346-0277-8
Hardcover ISBN
978-3-0346-0276-1
Softcover ISBN
978-3-0348-0316-8
Edition Number
1
Number of Pages
XIII, 447
Topics