Milestones in Drug Therapy

Glutamate-based Therapies for Psychiatric Disorders

Editors: Skolnick, Phil (Ed.)

  • Contemporary monograph on glutamate-based approaches to treat psychiatric drugs The approaches described in this text exploit both metabotropic and ionotropic glutamate receptors Focus on translational research, with many of the authors coming from industry All are acknowledged authorities in the glutamate field

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eBook $229.00
price for USA (gross)
  • ISBN 978-3-0346-0241-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-3-0346-0240-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Both metabotropic and ionotropic glutamate receptors present attractive “druggable” targets in treating disorders of the central nervous system. There has been a dramatic shift in the focus of glutamate-based therapies away from neurologic disorders such as stroke and traumatic brain injury to the treatment of psychiatric disorders. This “Milestones in Drug Therapy” volume offers a unique, contemporary overview of preclinical and clinical evidence that modulating glutamatergic tone is an effective means of treating psychiatric disorders ranging from depression and anxiety to schizophrenia and drug abuse. The ability to treat diseases such as depression and schizophrenia through multiple, glutamate-based mechanisms offers a unique therapeutic opportunity, as described in this book.

Reviews

From the reviews:

“This book summarizes the translational research in the development of glutamate-based approaches to treat psychiatric disorders. Written and edited by an international group of researchers, it is an important addition to the psychiatric literature. … The intended audience includes psychiatric researchers and psychiatrists. Neuroscientists interested in the treatment of patients with psychiatric disorders also would benefit from reading this book. … The index is quite helpful. … presents a unique and novel approach that is desperately needed in the treatment of these difficult disorders.” (Michael Joel Schrift, Doody’s Review Service, February, 2011)

Table of contents (9 chapters)

  • N-Methyl-d-Aspartate (NMDA) Antagonists for the Treatment of Depression

    Skolnick, Phil (et al.)

    Pages 1-20

  • Ionic Glutamate Modulators in Depression (Zinc, Magnesium)

    Szewczyk, Bernadeta (et al.)

    Pages 21-38

  • Positive Allosteric Modulation of AMPA Receptors: A Novel Potential Antidepressant Therapy

    Nisenbaum, Eric S. (et al.)

    Pages 39-56

  • Glutamatergic Modulators for the Treatment of Major Depressive Disorder: Metabotropic Glutamate Receptors

    Witkin, Jeffrey M.

    Pages 57-74

  • Positive Modulation of AMPA Receptors as a Broad-Spectrum Strategy for Treating Neuropsychiatric Disorders

    Lynch, Gary (et al.)

    Pages 75-100

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-3-0346-0241-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.00
price for USA
  • ISBN 978-3-0346-0240-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Glutamate-based Therapies for Psychiatric Disorders
Editors
  • Phil Skolnick
Series Title
Milestones in Drug Therapy
Copyright
2010
Publisher
Birkhäuser Basel
Copyright Holder
Springer Basel AG
eBook ISBN
978-3-0346-0241-9
DOI
10.1007/978-3-0346-0241-9
Hardcover ISBN
978-3-0346-0240-2
Series ISSN
2296-6056
Edition Number
1
Number of Pages
XIV, 178
Topics