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GABA and Sleep

Molecular, Functional and Clinical Aspects

Editors: Monti, Jaime M., Pandi-Perumal, Seithikurippu Ratnas, Möhler, Hanns (Eds.)

  • Focuses on the neuropsychopharmacology of GABA and its role in sleep and wakefulness
  • Presents neurochemical, electrophysiological, and neuropharmacological approaches to understand GABAergic mechanisms
  • Offers an overview of current approaches and medications
  • Features contributing authors who are leading experts in the field of sleep and neuropharmacology
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eBook $219.00
price for USA (gross)
  • ISBN 978-3-0346-0226-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-3-0346-0225-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-3-0348-0740-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

GABA (gamma-aminobutyric acid) is the main neurotransmitter regulating sleep. The majority of drugs presently in use for the treatment of sleep disorders act by enhancing GABAergic neuronal inhibition. This book brings together many of the world’s leading investigators to discuss current and anticipated developments in the areas of geriatric sleep medicine and provides a comprehensive examination of current principles and practice in this field. It is divided into three main sections: Section I: Basic Physiology and Pharmacology Section II: Sleep Science and Circuitry Section III: Neurotherapeutics The areas covered include findings from research investigations various aspects of GABAergic systems and the regulation of sleep. The book is suitable for basic and clinical neuropharmacologists, sleep researchers, psychiatrists, sleep disorders specialists, clinicians, medical students, and all professionals interested in the interdisciplinary areas of sleep and neuropharmacology.

Table of contents (20 chapters)

  • Physiology and Pharmacology of the GABA System: Focus on GABA Receptors

    Möhler, Hanns

    Pages 3-23

  • Development of Subtype-Selective GABAA Receptor Compounds for the Treatment of Anxiety, Sleep Disorders and Epilepsy

    Atack, John R.

    Pages 25-72

  • Distribution of GABAA Receptor Subunits in the Human Brain

    Waldvogel, H. J (et al.)

    Pages 73-93

  • Pharmacokinetic Determinants of the Clinical Effects of Benzodiazepine Agonist Hypnotics

    Greenblatt, David J.

    Pages 95-118

  • Sleep and Its Modulation by Substances That Affect GABAA Receptor Function

    Steiger, Axel

    Pages 121-146

Buy this book

eBook $219.00
price for USA (gross)
  • ISBN 978-3-0346-0226-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $279.00
price for USA
  • ISBN 978-3-0346-0225-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $279.00
price for USA
  • ISBN 978-3-0348-0740-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
GABA and Sleep
Book Subtitle
Molecular, Functional and Clinical Aspects
Editors
  • Jaime M. Monti
  • Seithikurippu Ratnas Pandi-Perumal
  • Hanns Möhler
Copyright
2010
Publisher
Springer Basel
Copyright Holder
Springer Basel AG
eBook ISBN
978-3-0346-0226-6
DOI
10.1007/978-3-0346-0226-6
Hardcover ISBN
978-3-0346-0225-9
Softcover ISBN
978-3-0348-0740-1
Edition Number
1
Number of Pages
XXIV, 486
Topics