Methods in Molecular Biology

Dynamic Brain Imaging

Multi-Modal Methods and In Vivo Applications

Editors: Fahmeed, Hyder (Ed.)

  • Provides a balanced emphasis on methods and applications that even specialists within various functional imaging fields will find useful
  • Contains a review of developments in technical features of dynamic multi-modal imaging and analytical tools for characterization of dynamic signals
  • Includes novel multi-modal applications in neuroimaging to epilepsy, with state-of-the-art demonstrations of increased sensitivity and specificity of detection
  • Examines examples of dynamic functional imaging of multiple brain areas (e.g., cerebral cortex, olfactory bulb, retina) using cutting-edge multi-modal techniques
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About this book

The developing of in vivo neuroscience techniques is rapidly improving the specificity and sensitivity of measurements of brain function. However, despite improvements in individual methods, it is becoming increasingly clear that the most effective research approaches will be multi-modal. Thus, it is the researchers who are familiar with many in vivo techniques who will be able to make the most substantial contributions to our understanding of dynamic brain function.

In Dynamic Brain Imaging: Multi-Modal Methods and In Vivo Applications, leading experts specializing in magnetic resonance, electrophysiology, and optical imaging methods explain basic principles of their respective techniques and demonstrate their power in depicting functional activation patterns en route to a basic understanding of the dynamic processes underlying various neuroimaging signals. The novel results, from various species, provide a new understanding of dynamics of neural activity that span a wide spatiotemporal range. Numerous cutting-edge applications are used as examples to illustrate enticing possibilities of combining techniques toward studies of normal function and disease. Exclusive examples of dynamic functional imaging of the cerebral cortex, olfactory bulb, and retina are used to demonstrate the effectiveness of each method for applications to the neurosciences. State-of-the-art techniques described include multi-photon optical imaging, multi-array electrical recordings, heteronuclear magnetic resonance spectroscopy and functional magnetic resonance imaging.

Up-to-date and user-friendly, Dynamic Brain Imaging: Multi-Modal Methods and In Vivo Applications is designed to be accessible to both specialist neurophysiologists and general neuroscientists. It reviews the fundamental, theoretical, and practical principles of magnetic resonance, electrophysiology, and optical methods as applied in the neurosciences and shows how these tools can be used successfully to answer important questions in brain science.

Reviews

From the reviews:

"The title follows a similar review of Dynamic Brain Imaging, with an emphasis on methods and protocols. The stated goal of this book is to ‘… help users learn to decipher the dynamic imaging data.’ … Overall … chapters were well written and accomplished their intended goal of educating the reader about the various dynamic imaging methodologies at various stages of development. … In summary, this review of multimodal in vivo brain imaging methods provides a nice compilation of manuscripts … ." (American Journal of Neuroradiology, Vol. 30, May, 2009)


Table of contents (15 chapters)

  • Dynamic Imaging of Brain Function

    Hyder, Fahmeed

    Pages 3-21

  • Fractal Characterization of Complexity in Dynamic Signals: Application to Cerebral Hemodynamics

    Herman, Peter (et al.)

    Pages 23-40

  • Wide-Field and Two-Photon Imaging of Brain Activity with Voltage and Calcium-Sensitive Dyes

    Homma, Ryota (et al.)

    Pages 43-79

  • Two-Photon Imaging of Capillary Blood Flow in Olfactory Bulb Glomeruli

    Tiret, Pascale (et al.)

    Pages 81-91

  • Astrocytic Calcium Signaling: Mechanism and Implications for Functional Brain Imaging

    Wang, Xiaohai (et al.)

    Pages 93-109

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-59745-543-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-934115-74-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.00
price for USA
  • ISBN 978-1-62703-881-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Dynamic Brain Imaging
Book Subtitle
Multi-Modal Methods and In Vivo Applications
Editors
  • Hyder Fahmeed
Series Title
Methods in Molecular Biology
Series Volume
489
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-543-5
DOI
10.1007/978-1-59745-543-5
Hardcover ISBN
978-1-934115-74-9
Softcover ISBN
978-1-62703-881-2
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XVIII, 379
Topics