Methods in Molecular Biology

Meiosis

Volume 1, Molecular and Genetic Methods

Editors: Keeney, Scott (Ed.)

  • Offers state-of-the-art techniques for analysis of meiotic recombination
  • Contains comprehensive methods for studying meiosis in human and in many commonly used model organisms
  • Includes chapters on background theory, methodology, and statistical considerations for classical genetic analysis of recombination and crossover interference
  • Presents cutting-edge methods for the direct detection, quantification, and characterization of the DNA intermediates and products of the recombination pathway
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eBook $149.00
price for USA (gross)
  • ISBN 978-1-59745-527-5
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  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-1-934115-66-4
  • Free shipping for individuals worldwide
  • This title is currently reprinting. You can pre-order your copy now.
Softcover $199.00
price for USA
  • ISBN 978-1-4939-6157-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The unique chromosome dynamics of meiosis have fascinated scientists for well over a century, but in recent years there has been a proliferation of new data concerning the pairing, recombination, and segregation of chromosomes. In Meiosis, expert researchers explore recent advances in three main areas: quantitative genetic methods for analysis of homologous recombination and chromosome pairing, development of direct physical assays for DNA intermediates and products of recombination, and cytological methods for characterizing chromosome behaviors and the patterns by which specific proteins associate with meiotic chromosomes. Meiosis: Volume 1, Molecular and Genetic Methods details methods for culturing and manipulating commonly used model organisms and protocols for detecting and quantifying meiotic recombination events through genetic and physical analysis of DNA-DNA or Protein-DNA interactions. Methods are provided for studies in yeasts, plants, and animals, including mouse and human. Composed in the highly successful Methods in Molecular Biology(tm) series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Comprehensive and cutting-edge, Meiosis: Volume 1, Molecular and Genetic Methods is an essential guidebook, providing up-to-date and critical new protocols for the study of meiotic chromosome dynamics.

Table of contents (20 chapters)

  • Interaction of Genetic and Environmental Factors in Saccharomyces cerevisiae Meiosis: The Devil is in the Details

    Cotton, Victoria E. (et al.)

    Pages 3-20

  • Optimizing Sporulation Conditions for Different Saccharomyces cerevisiae Strain Backgrounds

    Elrod, Susan L. (et al.)

    Pages 21-26

  • Modulating and Targeting Meiotic Double-Strand Breaks in Saccharomyces cerevisiae

    Nicolas, Alain

    Pages 27-33

  • Methods for Analysis of Crossover Interference in Saccharomyces cerevisiae

    Stahl, Franklin W. (et al.)

    Pages 35-53

  • Measurement of Spatial Proximity and Accessibility of Chromosomal Loci in Saccharomyces cerevisiae Using Cre /loxP Site-Specific Recombination

    Lui, Doris (et al.)

    Pages 55-63

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-59745-527-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.00
price for USA
  • ISBN 978-1-934115-66-4
  • Free shipping for individuals worldwide
  • This title is currently reprinting. You can pre-order your copy now.
Softcover $199.00
price for USA
  • ISBN 978-1-4939-6157-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Meiosis
Book Subtitle
Volume 1, Molecular and Genetic Methods
Editors
  • Scott Keeney
Series Title
Methods in Molecular Biology
Series Volume
557
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-527-5
DOI
10.1007/978-1-59745-527-5
Hardcover ISBN
978-1-934115-66-4
Softcover ISBN
978-1-4939-6157-3
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 365
Topics