Principles of Molecular Oncology

Editors: Bronchud, M.H., Foote, M., Giaccone, G., Olopade, O.I., Workman, P. (Eds.)

  • Comprehensive, up-to-date review of the molecular basis of cancer
  • Cutting-edge insights from genomics, proteomics, and new chemoprevention strategies
  • Includes discussion of new therapeutic monoclonal antibodies
  • Covers new cytotoxic or cytostatic small-molecular-weight compounds
  • Describes emerging molecular targets and current drugs under development
  • Provides a multidisciplinary perspective by recognized authorities from across the US and Europe
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eBook $189.00
price for USA (gross)
  • ISBN 978-1-59745-470-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-934115-25-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Drawing on years of significant scientific advances and clinical developments, the editors of POMO III have thoroughly updated the highly praised first and second editions and added new chapters to reflect the knowledge emerging from research on genomics, proteomics, chemoprevention strategies, pharmacogenomics, new molecular targets, therapeutic monoclonal antibodies, and innovative cytotoxic and cytostatic small molecular-weight molecules. The first edition of this book (Humana Press, 2000) was also the first comprehensive presentation of the concept of cancer as a "disease process" involving key regulatory pathways. The second edition (2004) reaffirmed this dynamic concept, incorporating more recent evidence, and introducing such new topics of special interest as the combination of molecular diagnostics-expression profiling of genes and proteins- with developmental therapeutics, and the "binary state" concept (active/inactive) that seeks more relevant targets within the global molecular matrix of a given cancer. Comprehensive and intellectually stimulating, POMO III not only clearly elucidates the fundamentals of this dramatically advancing field, but also interprets the vast and often complex molecular data available. It fills a much neglected gap between "information" and "knowledge," and holds out the hope of new anticancer strategies that will reduce the process of carcinogenesis, cancer cell proliferation and significantly reduce metastasis.

Reviews

From the reviews of the third edition:

"This is an update of a book of individual reviews of molecular oncology topics written by specialists in the field. … The intention is to present a broad overview of the concepts in molecular medicine and tumor biology that form the basis of many ongoing drug discovery projects … . The book is written for a broad audience, including students, house officers and clinical fellows, beginning researchers in cancer biology, and even practitioners of oncology." (Alexander C Minella, Doody’s Review Service, 2008)

"The book provides a comprehensive and in-depth view of molecular basis of cancer. … it is a valuable resource of knowledge for both clinical and experimental oncologists. Those who are interested in the basic understanding of great progress which has been achieved in molecular oncology in last year will enjoy this book as well." (C. Altaner, Neoplasma, September, 2008)


Table of contents (20 chapters)

  • Selecting the Right Targets for Cancer Therapy

    Bronchud, Miguel H.

    Pages 1-26

  • Clinical Importance of Prognostic Factors

    Henry, N. Lynn (et al.)

    Pages 27-41

  • Genetic Markers in Sporadic Tumors

    Tamborini, Elena (et al.)

    Pages 43-84

  • Genetic Markers in Breast Tumors with Hereditary Predisposition

    Grushko, Tatyana A. (et al.)

    Pages 85-105

  • Circulating Tumor Markers

    Horwich, Alan (et al.)

    Pages 107-116

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-59745-470-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-934115-25-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Principles of Molecular Oncology
Editors
  • Miguel H. Bronchud
  • MaryAnn Foote
  • Giuseppe Giaccone
  • Olufunmilayo I. Olopade
  • Paul Workman
Copyright
2008
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-470-4
DOI
10.1007/978-1-59745-470-4
Hardcover ISBN
978-1-934115-25-1
Edition Number
3
Number of Pages
XX, 420
Number of Illustrations and Tables
64 b/w illustrations, 21 illustrations in colour
Topics