Cellular Respiration and Carcinogenesis

Editors: Apte, Shireesh, Sarangarajan, Rangaprasad (Eds.)

  • Provides first glimpse into cutting-edge research
  • Opens a new dialogue in regards to the Warburg hypothesis
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eBook $179.00
price for USA (gross)
  • ISBN 978-1-59745-435-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-1-934115-07-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-1-62703-941-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Cellular Respiration and Carcinogenesis informs the reader about both basic and recent research in the field of cellular respiration and the effects of its dysfunction, alteration or attenuation on the development of cancer. This masterfully compiled text by leading experts in the field, offers the reader a fundamental understanding about how oxygen sensing and/or availability, programmed cell death, immune recognition and response and glucose metabolism are intimately linked with the two major mechanisms or pathways of cellular respiration; oxidative phosphorylation and glycolysis.  The editors and contributing authors proficiently and unequivocally address the effects of dysfunction of the mitochondrial oxidative phosphorylation/glycolysis (cellular respiration) mechanisms and pathways on the development of cancer. While it remains true that there are no universal truths in cancer, Cellular Respiration and Carcinogenesis opens the dialogue that the etiology of cancer can usually be associated with and significantly attributed to the failure of one or multiple pathways of oxidative phosphorylation to normally burn fuel to generate energy, vis-à-vis the Warburg hypothesis. Keeping with its cutting-edge nature, Cellular Respiration and Carcinogenesis provides the first glimpse of cautionary evidence based counterbalance to the recent and rapidly proliferating notion that utilization of fuel primarily via glycolysis is a hallmark of cancer development.

 

 

About the Editors:

Shireesh P.Apte, Ph.D has 10+ years experience in the pharmaceutical industry researching and formulating anti-cancer drugs. He holds one US patent and has 10+ related publications. He is a member of the US Pharmacopoeia excipients expert committee.

Rangaprasad Sarangarajan, Ph.D. has over 10 years of research experience in an academic setting with extensive publications in areas of pharmacology & toxicology with focus on cancer treatment.  He is active member of various professional organizations including the Society of Toxicology, American Society for Pharmacology & Toxicology and Pan American Society for Pigment Cell Research.

Reviews

From the reviews:

"It includes 12 chapters on topics ranging from the regulation of glucose metabolism in neoplastic cells … . The book is written for clinical and basic science researchers across a wide range of life science disciplines … . Students and experts … will appreciate this thoughtful and stimulating review of the field. … This book captures the excitement of the field. This is the book to have if you are interested in glucose metabolism, oxygen utilization, ATP, mitochondrial function, apoptosis, and cancer." (Bruce A. Fenderson, Doody’s Review Service, May, 2009)


Table of contents (12 chapters)

  • Oxidative Phosphorylation and Cancer: The Ongoing Warburg Hypothesis

    Ristow, Michael (et al.)

    Pages 1-18

  • How Cancer Cells Escape Death

    Werner, Erica

    Pages 1-18

  • The Electron Transport Chain and Carcinogenesis

    Brière, Jean-Jacques (et al.)

    Pages 19-32

  • Respiratory Control of Redox Signaling and Cancer

    Carrico, Pauline M. (et al.)

    Pages 33-44

  • Cellular Respiration and Dedifferentiation

    Scatena, Roberto (et al.)

    Pages 45-54

Buy this book

eBook $179.00
price for USA (gross)
  • ISBN 978-1-59745-435-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $229.00
price for USA
  • ISBN 978-1-934115-07-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $229.00
price for USA
  • ISBN 978-1-62703-941-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cellular Respiration and Carcinogenesis
Editors
  • Shireesh Apte
  • Rangaprasad Sarangarajan
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-435-3
DOI
10.1007/978-1-59745-435-3
Hardcover ISBN
978-1-934115-07-7
Softcover ISBN
978-1-62703-941-3
Edition Number
1
Number of Pages
XI, 195
Topics