Topics in Bone Biology

Bone Resorption

Editors: Bronner, Felix, Farach-Carson, Mary C., Rubin, Janet (Eds.)

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About this book

Bone Resorption, the second volume in the series Topics in Bone Biology, deals with the osteoclast, the bone-resorbing cell, its origins, its enzymes, the regulation of osteoclast activity, and structural aspects of bone resorption. Diseases involving osteoclast function are discussed from the genetic viewpoint in two chapters that span transgenic mouse models to human pathology. Another chapter treats diseases of osteoclast function. Because osteoporosis may be considered a disease in which the bone resorption rate exceeds formation, a separate chapter deals with current and potential therapeutic approaches to this widespread disease that affects both men and women. Bone metastases and an analysis of the central role of the osteoclast in this condition are treated in the concluding chapter.

The reviews in the book are essential reading for clinicians, researchers and students in a variety of fields: skeletal biology and orthopedics, nutrition, rheumatology, endocrinology, nephrology, oncology, dentistry, nursing, and chiropractic medicine. Together with the earlier volume on Bone Formation, this volumes serves as a beacon to a field that has become a major topic for those who study the health concerns of the aged, the very young, athletes and those with cancer.

Reviews

From the reviews:

"Volume 2 in the series Bone Biology and written by US experts, it reviews in 9 chapters the biology, physiology and physiopathology of the osteoclast. It also describes the new drugs which inhibit bone resorption. A very complete, well referenced text, of interest to all who research or treat bone diseases, including pediatric endocrinologists." (Zvi Laron, Pediatric Endocrinology Reviews, Vol. 3 (2), 2005)


Table of contents (5 chapters)

  • Osteoclast: Origin and Differentiation

    Janet Rubin, Edward M. Greenfield

    Pages 1-23

  • Regulation of Osteoclast Activity

    Roland Baron, William C. Horne

    Pages 34-57

  • Structural Aspects of Bone Resorption

    Steven D. Bain, Ted S. Gross

    Pages 58-66

  • Inflammatory Cytokines

    Mark S. Nanes, Roberto Pacifici

    Pages 67-90

  • Clinical Disorders Associated with Alterations in Bone Resorption

    Janet Rubin, Mark S. Nanes

    Pages 108-127

Buy this book

eBook $229.00
price for USA (gross)
  • ISBN 978-1-84628-016-0
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $289.00
price for USA
  • ISBN 978-1-85233-812-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $289.00
price for USA
  • ISBN 978-1-84996-926-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Bone Resorption
Editors
  • Felix Bronner
  • Mary C. Farach-Carson
  • Janet Rubin
Series Title
Topics in Bone Biology
Series Volume
2
Copyright
2005
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London
eBook ISBN
978-1-84628-016-0
DOI
10.1007/b136184
Hardcover ISBN
978-1-85233-812-1
Softcover ISBN
978-1-84996-926-0
Series ISSN
2199-2436
Edition Number
1
Number of Pages
XIV, 190
Topics