Methods in Molecular Biology

Therapeutic Applications of Ribozymes and Riboswitches

Methods and Protocols

Editors: Lafontaine, Daniel A, Dubé, Audrey (Eds.)

  • An overview of protocols used int the development of RNA molecule as drugs and drug target
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $89.00
price for USA (gross)
  • ISBN 978-1-62703-730-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $119.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-62703-729-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-4939-6296-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

In Therapeutic Applications of Ribozymes and Riboswitches: Methods and Protocols, expert researchers in the field provide a complete overview of protocols used in the development of RNA molecule as drugs and drug target. These include methods and protocols on recent and precise RNA molecule approaches or studies in the development of an RNA therapeutic tool. We are convinced that these methods will help researchers from various domains of life sciences, including clinicians, biochemists and virologists. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Therapeutic Applications of Ribozymes and Riboswitches: Methods and Protocols seeks to aid scientists in the further development of new therapeutic applications implicating RNA molecules or directly targeting harmful RNA.

Table of contents (19 chapters)

  • Identification of Regulatory RNA in Bacterial Genomes by Genome-Scale Mapping of Transcription Start Sites

    Singh, Navjot (et al.)

    Pages 1-10

  • Screening Inhibitory Potential of Anti-HIV RT RNA Aptamers

    Lange, Margaret J. (et al.)

    Pages 11-29

  • Design and Evaluation of Clinically Relevant SOFA-HDV Ribozymes Targeting HIV RNA

    Scarborough, Robert J. (et al.)

    Pages 31-43

  • Directing RNase P-Mediated Cleavage of Target mRNAs by Engineered External Guide Sequences in Cultured Cells

    Jiang, Xiaohong (et al.)

    Pages 45-56

  • Design and Analysis of Hammerhead Ribozyme Activity Against an Artificial Gene Target

    Carter, James R. (et al.)

    Pages 57-66

Buy this book

eBook $89.00
price for USA (gross)
  • ISBN 978-1-62703-730-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $119.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-62703-729-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-4939-6296-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Therapeutic Applications of Ribozymes and Riboswitches
Book Subtitle
Methods and Protocols
Editors
  • Daniel A Lafontaine
  • Audrey Dubé
Series Title
Methods in Molecular Biology
Series Volume
1103
Copyright
2014
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, New York
eBook ISBN
978-1-62703-730-3
DOI
10.1007/978-1-62703-730-3
Hardcover ISBN
978-1-62703-729-7
Softcover ISBN
978-1-4939-6296-9
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 278
Number of Illustrations and Tables
34 b/w illustrations, 19 illustrations in colour
Topics