Methods in Molecular Biology

Gene Function Analysis

Editors: Ochs, Michael F. (Ed.)

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $109.00
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  • ISBN 978-1-62703-721-1
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Hardcover $139.00
price for USA
  • ISBN 978-1-62703-720-4
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Softcover $139.00
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About this book

The determination of protein function has been a major goal of molecular biology since the founding of the discipline. However, as we learn more about gene function, we discover that the context within which a gene is expressed controls the specific function of that gene. It has become critical to establish the background in which gene function is determined and to perform experiments in multiple applicable backgrounds. In Gene Function Analysis, Second Edition, a number of computational and experimental techniques are presented for identifying not only the function of an individual gene, but also the partners that work with that gene. The theme of data integration runs strongly through the computational techniques, with many focusing on gathering data from different sources and different biomolecular types. Experimental techniques have evolved to determine function in specific tissues and at specific times during development. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Gene Function Analysis, Second Edition seeks to serve both professionals and novices with a growing understanding of the complexity of gene function.

Table of contents (19 chapters)

  • The Present State and Future Direction of Integrated Gene Function Analysis

    Ochs, Michael F.

    Pages 3-9

  • Performing Integrative Functional Genomics Analysis in GeneWeaver.org

    Jay, Jeremy J. (et al.)

    Pages 13-29

  • Functional Annotation of Differentially Regulated Gene Set Using WebGestalt: A Gene Set Predictive of Response to Ipilimumab in Tumor Biopsies

    Kirov, Stefan (et al.)

    Pages 31-42

  • Integrative Data-Mining Tools to Link Gene and Function

    Yacoubi, Basma (et al.)

    Pages 43-66

  • Detection of Driver Protein Complexes in Breast Cancer Metastasis by Large-Scale Transcriptome–Interactome Integration

    Garcia, Maxime (et al.)

    Pages 67-85

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-62703-721-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-62703-720-4
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4939-6063-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Gene Function Analysis
Editors
  • Michael F. Ochs
Series Title
Methods in Molecular Biology
Series Volume
1101
Copyright
2014
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
Distribution Rights
Distribution rights for India: CBS Publishers, New Delhi, India
eBook ISBN
978-1-62703-721-1
DOI
10.1007/978-1-62703-721-1
Hardcover ISBN
978-1-62703-720-4
Softcover ISBN
978-1-4939-6063-7
Series ISSN
1064-3745
Edition Number
2
Number of Pages
XIII, 416
Number of Illustrations and Tables
37 b/w illustrations, 86 illustrations in colour
Topics