Methods in Molecular Biology

RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods

Editors: Gorodkin, Jan, Ruzzo, Walter L. (Eds.)

  • Presents current up-to-date methodologies
  • Features tips on trouble shooting and avoiding known pitfalls
  • Contains key notes and implementation advice from the experts
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eBook $109.00
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  • ISBN 978-1-62703-709-9
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Hardcover $139.00
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  • ISBN 978-1-62703-708-2
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Softcover $139.00
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  • ISBN 978-1-4939-6165-8
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About this book

The existence of genes for RNA molecules not coding for proteins (ncRNAs) has been recognized since the 1950's, but until recently, aside from the critically important ribosomal and transfer RNA genes, most focus has been on protein coding genes.  However, a long series of striking discoveries, from RNA's ability to carry out catalytic function, to discovery of riboswitches, microRNAs and other ribo-regulators performing critical tasks in essentially all living organisms, has created a burgeoning interest in this primordial component of the biosphere.  However, the structural characteristics and evolutionary constraints on RNA molecules are very different from those of proteins, necessitating development of a completely new suite of informatic tools to address these challenges. In RNA Sequence, Structure, Function: Computational and Bioinformatic Methods, expert researchers in the field describe a substantial and relevant fraction of these methodologies from both practical and computational/algorithmic perspectives. Focusing on both of these directions addresses both the biologist interested in knowing more about RNA bioinformatics as well as the bioinformaticist interested in more detailed aspects of the algorithms.  Written in the highly successful Methods in Molecular Biology series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results.

 

Thorough and intuitive, RNA Sequence, Structure, Function: Computational and Bioinformatic Methods aids scientists in continuing to study key methods and principles of RNA bioinformatics.

Reviews

From the book reviews:

“This book on RNA structure and function is suitable for both graduate and post-graduate students as well as established researchers. … the book is also a valuable review of the state of the art of hot topics on cutting edge directions of research. In addition, the value of each chapter is enriched by an extensive set of references of recent yet established papers, offering a reliable starting point for literature on each research topic.” (Irina Ioana Mohorianu, zbMATH 1307.92008, 2015)


Table of contents (23 chapters)

  • Concepts and Introduction to RNA Bioinformatics

    Gorodkin, Jan (et al.)

    Pages 1-31

  • The Principles of RNA Structure Architecture

    Zwieb, Christian

    Pages 33-43

  • The Determination of RNA Folding Nearest Neighbor Parameters

    Andronescu, Mirela (et al.)

    Pages 45-70

  • Energy-Directed RNA Structure Prediction

    Hofacker, Ivo L.

    Pages 71-84

  • Introduction to Stochastic Context Free Grammars

    Giegerich, Robert

    Pages 85-106

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-62703-709-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-62703-708-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4939-6165-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
RNA Sequence, Structure, and Function: Computational and Bioinformatic Methods
Editors
  • Jan Gorodkin
  • Walter L. Ruzzo
Series Title
Methods in Molecular Biology
Series Volume
1097
Copyright
2014
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
Distribution Rights
Distribution rights for India: Researchco Book Centre, New Delhi, India
eBook ISBN
978-1-62703-709-9
DOI
10.1007/978-1-62703-709-9
Hardcover ISBN
978-1-62703-708-2
Softcover ISBN
978-1-4939-6165-8
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 533
Number of Illustrations and Tables
74 b/w illustrations, 46 illustrations in colour
Topics