Skip to main content
  • Book
  • © 2014

Therapeutic Peptides

Methods and Protocols

Editors:

  • Features methods for the identification of peptide therapeutic candidates through a wide variety of techniques
  • Includes step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1088)

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 119.00
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

This is a preview of subscription content, log in via an institution to check for access.

Table of contents (18 protocols)

  1. Front Matter

    Pages i-xi
  2. Construction of a Filamentous Phage Display Peptide Library

    • Annette Fagerlund, Astrid Hilde Myrset, Mari Ann Kulseth
    Pages 19-33
  3. Engineering Bioactive Peptide-Based Therapeutic Molecules

    • Jong Sang Ryu, A. Yeon Cho, Sang Won Seo, Hosung Min
    Pages 35-50
  4. Affinity Selection Using Filamentous Phage Display

    • Mari Ann Kulseth, Annette Fagerlund, Astrid Hilde Myrset
    Pages 67-80
  5. Bioprospecting Open Reading Frames for Peptide Effectors

    • Ling Xiong, Charles Scott
    Pages 81-96
  6. Identification of Ideal Peptides for Heterovalent Ligands

    • Ajay Shrivastava, Matthew von Wronski, Michael F. Tweedle, Adrian D. Nunn
    Pages 97-105
  7. Engineering Peptide Therapeutics Using MIMETIBODYâ„¢ Technology

    • Kristen Picha, Chichi Huang, Peter Bugelski, Karyn O’Neil
    Pages 125-145
  8. Evaluation of Peptides as Protease Inhibitors and Stimulators

    • Hannu Koistinen, Can Hekim, Ping Wu, Ale Närvänen, Ulf-HÃ¥kan Stenman
    Pages 147-158
  9. Assessment of Antimicrobial (Host Defense) Peptides as Anti-Cancer Agents

    • Susan Douglas, David W. Hoskin, Ashley L. Hilchie
    Pages 159-170
  10. Peptide Labelling Strategies for Imaging Agents

    • Tuulia Huhtala, Janne Weisell, Jussi Rytkönen, Ale Närvänen
    Pages 171-183
  11. Peptide Optimization and Conjugation Strategies in the Development of Molecularly Targeted Magnetic Resonance Imaging Contrast Agents

    • Andrew F. Kolodziej, Zhaoda Zhang, Kirsten Overoye-Chan, Vincent Jacques, Peter Caravan
    Pages 185-211
  12. Evaluation of Prenylated Peptides for Use in Cellular Imaging and Biochemical Analysis

    • Joshua D. Ochocki, Urule Igbavboa, W. Gibson Wood, Edgar A. Arriaga, Elizabeth V. Wattenberg, Mark D. Distefano
    Pages 213-223
  13. Ultraviolet Absorption Spectroscopy of Peptides

    • Mangala R. Liyanage, Kunal Bakshi, David B. Volkin, C. Russell Middaugh
    Pages 225-236
  14. Fluorescence Spectroscopy of Peptides

    • Mangala R. Liyanage, Kunal Bakshi, David B. Volkin, C. Russell Middaugh
    Pages 237-246
  15. Circular Dichroism of Peptides

    • Kunal Bakshi, Mangala R. Liyanage, David B. Volkin, C. Russell Middaugh
    Pages 247-253
  16. Fourier Transform Infrared Spectroscopy of Peptides

    • Kunal Bakshi, Mangala R. Liyanage, David B. Volkin, C. Russell Middaugh
    Pages 255-269
  17. Back Matter

    Pages 271-279

About this book

Therapeutic Peptides: Methods and Protocols features biological methods for the preparation of peptide phage display libraries using both filamentous and lytic phage.  With contributions from renowned authors in the field, the book also explores selection and screening of the prepared peptide libraries for peptides with the desired function and the subsequent characterization of the identified peptides.  Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Practical and dependable,  Therapeutic Peptides: Methods and Protocols is an ideal guide for researchers from all backgrounds seeking methods for the identification of therapeutic peptide candidates.

Editors and Affiliations

  • Dyax Corporation Discovery Research, Cambridge, USA

    Andrew E. Nixon

Bibliographic Information

  • Book Title: Therapeutic Peptides

  • Book Subtitle: Methods and Protocols

  • Editors: Andrew E. Nixon

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-62703-673-3

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2014

  • Hardcover ISBN: 978-1-62703-672-6Published: 22 October 2013

  • Softcover ISBN: 978-1-4939-5712-5Published: 23 August 2016

  • eBook ISBN: 978-1-62703-673-3Published: 21 October 2013

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XI, 279

  • Number of Illustrations: 45 b/w illustrations, 8 illustrations in colour

  • Topics: Pharmacology/Toxicology

Buy it now

Buying options

eBook USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 119.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 119.00
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access