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Membrane Proteins

Folding, Association, and Design

  • Book
  • © 2013

Overview

Editors:
  1. Giovanna Ghirlanda

    1. Dept. of Chemistry and Biochemistry, Arizona State University, Tempe, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Alessandro Senes

    1. Department of Biochemistry, University of Wisconsin, Madison, Madison, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Focuses on model systems for the study of structure, folding, and association of proteins in the membrane
  • Presents laboratory-ready protocols provided by experts in the field
  • Features key tips and implementation advice to ensure successful results

Part of the book series: Methods in Molecular Biology (MIMB, volume 1063)

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Table of contents (13 protocols)

  1. Front Matter

    Pages i-x
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  4. NMR Methods

    1. Front Matter

      Pages 143-143
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    2. Membrane Protein Structure Determination: Back to the Membrane

      • Yong Yao, Yi Ding, Ye Tian, Stanley J. Opella, Francesca M. Marassi
      Pages 145-158

    3. On the Role of NMR Spectroscopy for Characterization of Antimicrobial Peptides

      • Fernando Porcelli, Ayyalusamy Ramamoorthy, George Barany, Gianluigi Veglia
      Pages 159-180

  5. Engineering Approaches

    1. Front Matter

      Pages 181-181
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    2. Prediction and Design of Outer Membrane Protein–Protein Interactions

      • Vikas Nanda, Daniel Hsieh, Alexander Davis
      Pages 183-196

    3. Design of Transmembrane Peptides: Coping with Sticky Situations

      • Arianna Rath, Charles M. Deber
      Pages 197-210

    4. Engineering and Utilization of Reporter Cell Lines for Cell-Based Assays of Transmembrane Receptors

      • Matthew W. Lluis, Hang Yin
      Pages 211-225

    5. Fluorination in the Design of Membrane Protein Assemblies

      • Vijay M. Krishnamurthy, Krishna Kumar
      Pages 227-243

  6. Back Matter

    Pages 245-246
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Keywords

About this book

Focusing on model systems for the study of structure, folding, and association in the membrane, Membrane Proteins: Folding, Association, and Design presents an overview of methods that can be applied to these intricate systems. The volume is divided into four detailed sections, covering association of transmembrane helices, interactions with the lipid bilayer, NMR methods, as well as a variety of engineering approaches.  Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and practical, Membrane Proteins: Folding, Association, and Design serves as an ideal guide for researchers reaching for the tantalizing possibility of designing novel membrane proteins with tailored functionality.

Editors and Affiliations

  • Dept. of Chemistry and Biochemistry, Arizona State University, Tempe, USA

    Giovanna Ghirlanda

  • Department of Biochemistry, University of Wisconsin, Madison, Madison, USA

    Alessandro Senes

Bibliographic Information

  • Book Title: Membrane Proteins

  • Book Subtitle: Folding, Association, and Design

  • Editors: Giovanna Ghirlanda, Alessandro Senes

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-62703-583-5

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2013

  • Hardcover ISBN: 978-1-62703-582-8Published: 23 August 2013

  • Softcover ISBN: 978-1-4939-6021-7Published: 23 August 2016

  • eBook ISBN: 978-1-62703-583-5Published: 23 August 2013

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: X, 246

  • Number of Illustrations: 24 b/w illustrations, 37 illustrations in colour

  • Topics: Protein Science, Membrane Biology

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