Methods in Molecular Biology

Metabolomics Tools for Natural Product Discovery

Methods and Protocols

Editors: Roessner, Ute, Dias, Daniel Anthony (Eds.)

  • Includes cutting-edge methos and protocols
  • Provides step-by-step detail essential to reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $89.00
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  • ISBN 978-1-62703-577-4
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Hardcover $119.00
price for USA
  • ISBN 978-1-62703-576-7
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  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
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About this book

Classical natural product chemistry is transitioning to modern day metabolomics as a result of the advent of comprehensive analytical platforms and sensitive analytical instrumentation. Therefore, it is worthwhile to summarize recent developments with current analytical platforms and highlight how metabolomics is being integrated into this classical field to dereplicate and profile natural product extracts. Metabolomics Tools for Natural Product Discoveries: Methods and Protocols aims to unite diverse and recently developed methodologies and protocols in order to identify bioactive secondary metabolites for the purpose of drug discovery. Some topics covered in this volume include applications for the extraction of selected natural products from less common sources such as bryophytes and hard corals, various biological assays, comprehensive applications and strategies for GC-MS, LC-MS, and NMR, as well as protocols and strategies for the structure elucidation of isolated natural products.  Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and easily accessible Metabolomics Tools for Natural Product Discoveries: Methods and Protocols seeks to serve both professionals and research students with its well-honed methodologies for natural product isolation, biomarker discovery, dereplication, biological assays, and comprehensive metabolomic platforms available for high-throughput analyses.

Table of contents (20 chapters)

  • Bryophytes: Liverworts, Mosses, and Hornworts: Extraction and Isolation Procedures

    Asakawa, Yoshinori (et al.)

    Pages 1-20

  • Plant Tissue Extraction for Metabolomics

    Roessner, Ute (et al.)

    Pages 21-28

  • Detection of Polar Metabolites Through the Use of Gas Chromatography–Mass Spectrometry

    Souza, David P.

    Pages 29-37

  • A Robust GC-MS Method for the Quantitation of Fatty Acids in Biological Systems

    Jayasinghe, Nirupama Samanmalie (et al.)

    Pages 39-56

  • A Workflow from Untargeted LC-MS Profiling to Targeted Natural Product Isolation

    Callahan, Damien L. (et al.)

    Pages 57-70

Buy this book

eBook $89.00
price for USA (gross)
  • ISBN 978-1-62703-577-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $119.00
price for USA
  • ISBN 978-1-62703-576-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $119.00
price for USA
  • ISBN 978-1-4939-6301-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Metabolomics Tools for Natural Product Discovery
Book Subtitle
Methods and Protocols
Editors
  • Ute Roessner
  • Daniel Anthony Dias
Series Title
Methods in Molecular Biology
Series Volume
1055
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
Distribution Rights
Distribution rights for India: Mehul Book Sales, Mumbai, India
eBook ISBN
978-1-62703-577-4
DOI
10.1007/978-1-62703-577-4
Hardcover ISBN
978-1-62703-576-7
Softcover ISBN
978-1-4939-6301-0
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 311
Number of Illustrations and Tables
50 b/w illustrations, 33 illustrations in colour
Topics