Methods in Molecular Biology

Antibody-Drug Conjugates

Editors: Ducry, Laurent (Ed.)

  • Supports the development of innovative cancer treatments through ADC techniques
  • Provides step-by-step methodologies that are readily reproducible
  • Features expert tips and key implementation advice to ensure successful results
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eBook $109.00
price for USA (gross)
  • ISBN 978-1-62703-541-5
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  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-62703-540-8
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  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
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  • ISBN 978-1-4939-6026-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Antibody-drug conjugates (ADCs) represent a promising therapeutic approach for cancer patients by combining the antigen-targeting specificity of monoclonal antibodies (mAbs) with the cytotoxic potency of chemotherapeutic drugs.  In Antibody-Drug Conjugates, expert researchers provide detailed protocols for many of the key ADC techniques necessary for working in the field. These chapters and methodologies are aimed at the key tasks necessary to identify a suitable target, properly design the mAb, the linker and the payload, as well as to conjugate them in a reproducible and scalable fashion.  Written in the highly successful Methods in Molecular Biology™ format, these detailed chapters include the kind of practical implementation advice that guarantees quality results.

 

Authoritative and timely, Antibody-Drug Conjugates aims to further drive ADC development and thus help toward improving cancer treatments of the future.

Table of contents (20 chapters)

  • Antibody–Drug Conjugate (ADC) Clinical Pipeline: A Review

    Sassoon, Ingrid (et al.)

    Pages 1-27

  • Antibody–Drug Conjugate Target Selection: Critical Factors

    Bander, Neil H.

    Pages 29-40

  • Selecting an Optimal Antibody for Antibody–Drug Conjugate Therapy: Internalization and Intracellular Localization

    Harper, Jay (et al.)

    Pages 41-49

  • Antibody–Drug Conjugate Payloads

    Anderl, Jan (et al.)

    Pages 51-70

  • Linker Technologies for Antibody–Drug Conjugates

    Nolting, Birte

    Pages 71-100

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-62703-541-5
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-62703-540-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4939-6026-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Antibody-Drug Conjugates
Editors
  • Laurent Ducry
Series Title
Methods in Molecular Biology
Series Volume
1045
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-62703-541-5
DOI
10.1007/978-1-62703-541-5
Hardcover ISBN
978-1-62703-540-8
Softcover ISBN
978-1-4939-6026-2
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 317
Number of Illustrations and Tables
54 b/w illustrations, 42 illustrations in colour
Topics