Methods in Molecular Biology

Genotoxicity Assessment

Methods and Protocols

Editors: Dhawan, Alok, Bajpayee, Mahima (Eds.)

  • Describes comprehensive genetic toxicology protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $109.00
price for USA (gross)
  • ISBN 978-1-62703-529-3
  • Digitally watermarked, DRM-free
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  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-62703-528-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4939-6302-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Genetic toxicology is recognized by geneticists and researchers concerned with the genetic impact of man-made chemicals. In Genotoxicity Assessment: Methods and Protocols, expert researchers in the field provide comprehensive genetic toxicology protocols. These include in vitro and in vivo protocols on mutation assays, cytogenetic techniques, and primary DNA damage, assays in alternate to animal models, and updated ICH guidelines. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as key tips on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Genotoxicity Assessment: Methods and Protocols seeks to aid research students and scientists working in regulatory toxicology as well as biomedical, biochemical and pharmaceutical sciences.

Table of contents (24 chapters)

  • Bacterial Mutation Assays

    Zeiger, Errol

    Pages 3-26

  • In Vitro Mouse Lymphoma (L5178Y Tk +/− -3.7.2C) Forward Mutation Assay

    Schisler, Melissa R. (et al.)

    Pages 27-50

  • Erythrocyte-Based Pig-a Gene Mutation Assay

    Bemis, Jeffrey C. (et al.)

    Pages 51-77

  • Detection of In Vivo Mutation in the Hprt and Pig-a Genes of Rat Lymphocytes

    Dobrovolsky, Vasily N. (et al.)

    Pages 79-95

  • In Vivo cII, gpt, and Spi− Gene Mutation Assays in Transgenic Mice and Rats

    Manjanatha, Mugimane G. (et al.)

    Pages 97-119

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-62703-529-3
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-62703-528-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $139.00
price for USA
  • ISBN 978-1-4939-6302-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Genotoxicity Assessment
Book Subtitle
Methods and Protocols
Editors
  • Alok Dhawan
  • Mahima Bajpayee
Series Title
Methods in Molecular Biology
Series Volume
1044
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, New York
eBook ISBN
978-1-62703-529-3
DOI
10.1007/978-1-62703-529-3
Hardcover ISBN
978-1-62703-528-6
Softcover ISBN
978-1-4939-6302-7
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XV, 463
Number of Illustrations and Tables
44 b/w illustrations, 62 illustrations in colour
Topics