Peroxisome Proliferator-Activated Receptors

Discovery and Recent Advances

Authors: Youssef, Jihan A., Badr, Mostafa Z.

  • Traces PPAR discovery through its history and to its modern state
  • Paves the way for the development of safer and more effective PPAR modulators as therapeutic agents
  • Serves as an excellent companion to Volume 952 of the Methods in Molecular Biology series
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Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-62703-420-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-62703-419-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

All three peroxisome proliferator-activated receptor (PPAR) subtypes share a high degree of structural homology while exhibiting differences in function, tissue distribution, and ligand specificity. In Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances, the authors trace the history of PPAR discovery and detail the receptor structure and its posttranslational modifications. Furthermore, endogenous ligands as well as various classes of exogenous ligands, subtype-selective, dual and pan agonists as well as antagonists, are discussed. In addition, the tissue distribution and versatile functions of PPAR subtypes in major organs are described.

 

As PPARs play critical roles as regulators of numerous physiological as well as pathophysiological pathways, Peroxisome Proliferator-Activated Receptors: Discovery and Recent Advances aims to help researchers to develop safer and more effective PPAR modulators as therapeutic agents to treat a myriad of diseases and conditions.

Table of contents (10 chapters)

  • Introduction

    Youssef, Jihan A. (et al.)

    Pages 1-3

  • History of PPAR Discovery

    Youssef, Jihan A. (et al.)

    Pages 5-14

  • Peroxisome Proliferator-Activated Receptors

    Youssef, Jihan A. (et al.)

    Pages 15-23

  • PPAR Ligands

    Youssef, Jihan A. (et al.)

    Pages 25-32

  • Tissue Distribution and Versatile Functions of PPARs

    Youssef, Jihan A. (et al.)

    Pages 33-69

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-62703-420-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
  • ISBN 978-1-62703-419-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Peroxisome Proliferator-Activated Receptors
Book Subtitle
Discovery and Recent Advances
Authors
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-62703-420-3
DOI
10.1007/978-1-62703-420-3
Hardcover ISBN
978-1-62703-419-7
Edition Number
1
Number of Pages
IX, 137
Topics