Methods in Molecular Biology

Chemical Neurobiology

Methods and Protocols

Editors: Banghart, Matthew R. (Ed.)

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $109.00
price for USA (gross)
  • ISBN 978-1-62703-345-9
  • Digitally watermarked, DRM-free
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  • Immediate eBook download after purchase
Hardcover $139.00
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  • ISBN 978-1-62703-344-2
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About this book

Many advances in modern neuroscience are enabled by the availability of chemical tools that allow sensitive, precise, and quantitative measurements of, and control over, biological processes. These powerful reagents are widely used for investigating the nervous system at levels of detail ranging from ion channel structure to neural network dynamics. Recent advances in photochemistry, microscopy, and protein engineering have triggered a surge in the development and application of these interdisciplinary techniques. Chemical Neurobiology: Methods and Protocols assists with the design, characterization and validation of new chemical tools for neurobiology by providing detailed protocols of procedures and assays deemed essential for the successful development and implementation of such tools. Divided into three sections, topics cover chemical probes of membrane protein structure and function, photochemical control of protein and cellular function, and chemical probes for imaging in the nervous system. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

 

Authoritative and easily accessible, Chemical Neurobiology: Methods and Protocols serves scientists at many levels, including students aiming to expand their perspective, laboratory researchers seeking technical guidance, and established investigators looking for creative solutions to their research problems in molecular, cellular and systems neuroscience. 

Table of contents (14 chapters)

  • Engineering K+ Channels Using Semisynthesis

    Komarov, Alexander G. (et al.)

    Pages 3-17

  • Chemical Derivatization and Purification of Peptide-Toxins for Probing Ion Channel Complexes

    Hua, Zhengmao (et al.)

    Pages 19-30

  • Using Yeast to Study Potassium Channel Function and Interactions with Small Molecules

    Bagriantsev, Sviatoslav N. (et al.)

    Pages 31-42

  • A FLIPR Assay for Evaluating Agonists and Antagonists of GPCR Heterodimers

    Harvey, Jessica H. (et al.)

    Pages 43-54

  • Characterizing Caged Molecules Through Flash Photolysis and Transient Absorption Spectroscopy

    Kao, Joseph P. Y. (et al.)

    Pages 57-77

Buy this book

eBook $109.00
price for USA (gross)
  • ISBN 978-1-62703-345-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.00
price for USA
  • ISBN 978-1-62703-344-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Chemical Neurobiology
Book Subtitle
Methods and Protocols
Editors
  • Matthew R. Banghart
Series Title
Methods in Molecular Biology
Series Volume
995
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-62703-345-9
DOI
10.1007/978-1-62703-345-9
Hardcover ISBN
978-1-62703-344-2
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 202
Topics