Methods in Molecular Biology

Calcium-Binding Proteins and RAGE

From Structural Basics to Clinical Applications

Editors: Heizmann, Claus W. (Ed.)

  • Underlines the diagnostic and clinical importance of this family of proteins in human diseases
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $129.00
price for USA (gross)
  • ISBN 978-1-62703-230-8
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  • Included format: EPUB, PDF
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  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-62703-229-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-4939-5976-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

A major direction in medical research leading to clinical applications  targets the regulation of intracellular calcium and the various human diseases associated with an altered homeostasis of this global second messenger. These diseases include, for example: cardiomyopathy, inflammation, brain disorders, diabetes and cancer. In Calcium-Binding Proteins and RAGE: from Structural Basics to Clinical Applications,expert researchers in the field detail many of the methods which are now commonly used to study calcium binding proteins. These methods and techniques, such as calcium-measurements, screening methods, clinical chemistry, and therapy, are generally applicable to many other areas of basic and medical research as well as to diagnostics. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and practical,Calcium-Binding Proteins and RAGE: from Structural Basics to Clinical Applications underlines the diagnostic and clinical importance of this family of proteins in human diseases and as drug targets.

Table of contents (25 chapters)

  • Measurement of Intracellular Ca2+ Concentration in Single Cells Using Ratiometric Calcium Dyes

    Srikanth, Sonal (et al.)

    Pages 3-14

  • Divers Models of Divalent Cation Interaction to Calcium-Binding Proteins: Techniques and Anthology

    Cox, Jos A.

    Pages 15-35

  • Probing Ca2+-Binding Capability of Viral Proteins with the EF-Hand Motif by Grafting Approach

    Zhou, Yubin (et al.)

    Pages 37-53

  • New Aspects of Calmodulin–Calmodulin Binding Domains Recognition

    Audran, Emilie (et al.)

    Pages 57-72

  • Purification and Characterization of the Human Cysteine-Rich S100A3 Protein and Its Pseudo Citrullinated Forms Expressed in Insect Cells

    Kizawa, Kenji (et al.)

    Pages 73-86

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-62703-230-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-62703-229-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-4939-5976-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Calcium-Binding Proteins and RAGE
Book Subtitle
From Structural Basics to Clinical Applications
Editors
  • Claus W. Heizmann
Series Title
Methods in Molecular Biology
Series Volume
963
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-62703-230-8
DOI
10.1007/978-1-62703-230-8
Hardcover ISBN
978-1-62703-229-2
Softcover ISBN
978-1-4939-5976-1
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIV, 424
Topics