Methods in Molecular Biology

Animal Models in Diabetes Research

Editors: Joost, Hans-Georg, Al-Hasani, Hadi, Schürmann, Annette (Eds.)

  • Emphasizes rodent strains that develop autoimmunity such as the NOD mouse, the Akita mouse, and the BB rat 
  • Features practical, cutting-edge protocols that are ready for the lab
  • Includes expert tips and key implementation advice to ensure successful results
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eBook $129.00
price for USA (gross)
  • ISBN 978-1-62703-068-7
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  • Immediate eBook download after purchase
Hardcover $169.00
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  • ISBN 978-1-62703-067-0
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About this book

In recent years, human studies have made enormous contributions towards an understanding of the genetic basis of diabetes mellitus; however, most of the experimentation needed for the invention and testing of novel therapeutic approaches cannot be performed in humans.  Thus, there is no alternative to appropriate animal models.  In Animal Models in Diabetes Research, expert researchers explore the current status of the most important models and procedures in order to provide a timely resource in experimental diabetology.  The first half of the volume serves as a comprehensive overview on our current knowledge of the pathogenesis and pathophysiology of diabetes in animal models through a series of reviews in model strains.  The book then continues with vital, established protocols that are employed in the characterization and study of animal models of diabetes.  As a volume in the highly successful Methods in Molecular Biology™ series, this work contains the type of detailed description and key implementation advice necessary to achieve successful results.

 

Authoritative and cutting-edge, Animal Models in Diabetes Research delivers essential content that will be an important resource to advance diabetes research in the years to come.

Table of contents (21 chapters)

  • The Non-Obese Diabetic (NOD) Mouse as a Model of Human Type 1 Diabetes

    Kachapati, Kritika (et al.)

    Pages 3-16

  • Assessment of Diabetic Nephropathy in the Akita Mouse

    Chang, Jae-Hyung (et al.)

    Pages 17-29

  • The BB Rat as a Model of Human Type 1 Diabetes

    Bortell, Rita (et al.)

    Pages 31-44

  • Diabetes in Mice with Monogenic Obesity: The db/db Mouse and Its Use in the Study of Cardiac Consequences

    Belke, Darrell D. (et al.)

    Pages 47-57

  • Pathophysiology and Genetics of Obesity and Diabetes in the New Zealand Obese Mouse: A Model of the Human Metabolic Syndrome

    Kluge, Reinhart (et al.)

    Pages 59-73

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-62703-068-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-62703-067-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Animal Models in Diabetes Research
Editors
  • Hans-Georg Joost
  • Hadi Al-Hasani
  • Annette Schürmann
Series Title
Methods in Molecular Biology
Series Volume
933
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-62703-068-7
DOI
10.1007/978-1-62703-068-7
Hardcover ISBN
978-1-62703-067-0
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 325
Topics