Methods in Molecular Biology

Computational Toxicology

Volume I

Editors: Reisfeld, Brad, Mayeno, Arthur N. (Eds.)

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $149.00
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  • ISBN 978-1-62703-050-2
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  • ISBN 978-1-62703-049-6
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About this book

Rapid advances in computer science, biology, chemistry, and other disciplines are enabling powerful new computational tools and models for toxicology and pharmacology. These computational tools hold tremendous promise for advancing science, from streamlining drug efficacy and safety testing, to increasing the efficiency and effectiveness of risk assessment for environmental chemicals. Computational Toxicology provides biomedical and quantitative scientists with essential background, context, examples, useful tips, and an overview of current developments in the field. Divided into four sections, Volume I covers a wide array of methodologies and topics. Opening with an introduction to the field of computational toxicology and its current and potential applications, the volume continues with ’best practices’ in mathematical and computational modeling, followed by chemoinformatics and the use of computational techniques and databases to predict chemical properties and toxicity, as well as an overview of molecular dynamics.  The final section is a compilation of the key elements and main approaches used in pharmacokinetic and pharmacodynamic modeling, including the modeling of absorption, compartment and non-compartmental modeling, physiologically based pharmacokinetic modeling, interspecies extrapolation, and population effects. Written in the successful Methods in Molecular Biology™ series format where possible, chapters include introductions to their respective topics, lists of the materials and software tools used, methods, and notes on troubleshooting.

Authoritative and easily accessible, Computational Toxicology will allow motivated readers to participate in this exciting field and undertake a diversity of realistic problems of interest.

Table of contents (21 chapters)

  • What is Computational Toxicology?

    Reisfeld, Brad (et al.)

    Pages 3-7

  • Computational Toxicology: Application in Environmental Chemicals

    Tan, Yu-Mei (et al.)

    Pages 9-19

  • Role of Computational Methods in Pharmaceutical Sciences

    Kortagere, Sandhya (et al.)

    Pages 21-48

  • Best Practices in Mathematical Modeling

    Pillis, Lisette G. de (et al.)

    Pages 51-74

  • Tools and Techniques

    Mayeno, Arthur N. (et al.)

    Pages 75-89

Buy this book

eBook $149.00
price for USA (gross)
  • ISBN 978-1-62703-050-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $189.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-62703-049-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Computational Toxicology
Book Subtitle
Volume I
Editors
  • Brad Reisfeld
  • Arthur N. Mayeno
Series Title
Methods in Molecular Biology
Series Volume
929
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
Distribution Rights
Distribution rights for India: Mehul Book Sales, Mumbai, India
eBook ISBN
978-1-62703-050-2
DOI
10.1007/978-1-62703-050-2
Hardcover ISBN
978-1-62703-049-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XII, 612
Topics