Methods in Molecular Biology

Clinical Applications of Capillary Electrophoresis

Methods and Protocols

Editors: Phillips, Terry M., Kalish, Heather (Eds.)

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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About this book

Capillary electrophoresis (CE) is a powerful and rapid tool for performing complex analyses of a number of different molecular species ranging from small inorganic ions to large nucleic acid fragments and proteins. It is quickly becoming established as a useful tool in clinical medicine due to its consumption of minute samples (less than a microlitre), low reagent costs, and extreme sensitivity, depending upon the source of detection used.  Clinical Applications of Capillary Electrophoresis aims to give an in-depth manual of CE applications in several important areas of clinical science.  Divided into seven sections, this volume provides a brief overview of how CE has been applied in clinical settings, followed by several chapters on CE analysis of important diagnostic molecules and biofluids, as well as descriptions of applications in clinical chemistry, hematology, bacteriology, virology, disease-associated biomarker discovery, immunology and genetic analysis. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Clinical Applications of Capillary Electrophoresis seeks to serve as a valuable source of information not only for clinical pathologists, but also clinical scientists who wish to apply the technique to diagnosis and research.

Table of contents (26 chapters)

  • An Overview of CE in Clinical Analysis

    Hage, David S.

    Pages 3-10

  • Monitoring of Arrays of Amino Acids in Clinical Samples Using Capillary Electrophoresis with Contactless Conductivity Detection

    Tůma, Petr (et al.)

    Pages 13-23

  • The Selective Determination of Sulfates, Sulfonates, and Phosphates in Urine by Capillary Electrophoresis/Mass Spectrometry

    Bunz, Svenja-Catharina (et al.)

    Pages 25-34

  • Analysis of Neurotransmitter Amino Acids by CE-LIF Detection in Biological Fluids

    Zinellu, Angelo (et al.)

    Pages 35-42

  • Expanded Newborn Screening of Inborn Errors of Metabolism by Capillary Electrophoresis-Electrospray Ionization-Mass Spectrometry (CE-ESI-MS)

    Britz-McKibbin, Philip

    Pages 43-56

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-62703-029-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-62703-028-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Clinical Applications of Capillary Electrophoresis
Book Subtitle
Methods and Protocols
Editors
  • Terry M. Phillips
  • Heather Kalish
Series Title
Methods in Molecular Biology
Series Volume
919
Copyright
2013
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-62703-029-8
DOI
10.1007/978-1-62703-029-8
Hardcover ISBN
978-1-62703-028-1
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIII, 311
Topics