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Contemporary Endocrinology

Ghrelin in Health and Disease

Editors: Smith, Roy G., Thorner, Michael O. (Eds.)

  • Superb overview of the relevance of ghrelin to physiology and as a modulator of function.
  • Covers all of the molecular and clinical issues, providing basic translational research on ghrelin with results of clinical investigations
  • Advances our clinical understanding of obesity, growth, and reproductive pathogenesis
  • Authored by leading international investigators in the field
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eBook $189.00
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  • ISBN 978-1-61779-903-7
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Hardcover $249.00
price for USA
  • ISBN 978-1-61779-902-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-62703-879-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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About this book

Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.

Table of contents (16 chapters)

  • Ghrelin: A History of Its Discovery

    Bowers, Cyril Y. (et al.)

    Pages 1-35

  • Enzymatic Processing of Ghrelin Precursor

    Kojima, Masayasu (et al.)

    Pages 37-49

  • Ghrelin’s Novel Signaling in Islet β-Cells to Inhibit Insulin Secretion and Its Blockade As a Promising Strategy to Treat Type 2 Diabetes

    Dezaki, Katsuya (et al.)

    Pages 51-71

  • Gastric Ghrelin in the Regulation of Appetite and Metabolism

    Seoane, Luisa María (et al.)

    Pages 73-89

  • Ghrelin Regulation of AMPK in the Hypothalamus and Peripheral Tissues

    Scerif, Miski (et al.)

    Pages 91-110

Buy this book

eBook $189.00
price for USA (gross)
  • ISBN 978-1-61779-903-7
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.00
price for USA
  • ISBN 978-1-61779-902-0
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.00
price for USA
  • ISBN 978-1-62703-879-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Rent the ebook  
  • Rental duration: 1 or 6 month
  • low-cost access
  • online reader with highlighting and note-making option
  • can be used across all devices
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Bibliographic Information

Bibliographic Information
Book Title
Ghrelin in Health and Disease
Editors
  • Roy G. Smith
  • Michael O. Thorner
Series Title
Contemporary Endocrinology
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media New York
eBook ISBN
978-1-61779-903-7
DOI
10.1007/978-1-61779-903-7
Hardcover ISBN
978-1-61779-902-0
Softcover ISBN
978-1-62703-879-9
Edition Number
1
Number of Pages
XIV, 290
Topics