Methods in Molecular Biology

Prenatal Gene Therapy

Concepts, Methods, and Protocols

Editors: Coutelle, Charles, Waddington, Simon N. (Eds.)

  • Aims at applying gene therapy during preganancy for the prevention of human diseases
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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eBook $129.00
price for USA (gross)
  • ISBN 978-1-61779-873-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-61779-872-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The emerging field of prenatal gene therapy is founded on scientific and technical advances in fetal medicine, molecular biology and gene therapy. This preclinical research subject aims at applying gene therapy during pregnancy for the prevention of human diseases caused by early onset congenital or gestation related conditions.  In Prenatal Gene Therapy: Concepts, Methods and Protocols, expert researchers in the field detail many of the protocols which are now commonly used to study gene therapy, fetal medicine and medical ethics. These include detailed protocols for vector production, for breeding and husbandry of the animal models, for  the surgical procedures of gene delivery in large and small animals and for the methods of gene transfer analysis. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

 

Thorough and intuitive, Prenatal Gene Therapy: Concepts, Methods and Protocols seeks to aid scientists in the further study of prenatal disease and gene therapy projects beyond the scope of fetal medicine.

Table of contents (17 chapters)

  • The Concept of Prenatal Gene Therapy

    Coutelle, Charles (et al.)

    Pages 1-7

  • Candidate Diseases for Prenatal Gene Therapy

    David, Anna L. (et al.)

    Pages 9-39

  • Vector Systems for Prenatal Gene Therapy: Choosing Vectors for Different Applications

    Coutelle, Charles (et al.)

    Pages 41-53

  • Vector Systems for Prenatal Gene Therapy: Principles of Adenovirus Design and Production

    Alba, Raul (et al.)

    Pages 55-84

  • Vector Systems for Prenatal Gene Therapy: Principles of Retrovirus Vector Design and Production

    Howe, Steven J. (et al.)

    Pages 85-107

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-61779-873-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
  • ISBN 978-1-61779-872-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Prenatal Gene Therapy
Book Subtitle
Concepts, Methods, and Protocols
Editors
  • Charles Coutelle
  • Simon N. Waddington
Series Title
Methods in Molecular Biology
Series Volume
891
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC.
eBook ISBN
978-1-61779-873-3
DOI
10.1007/978-1-61779-873-3
Hardcover ISBN
978-1-61779-872-6
Series ISSN
1064-3745
Edition Number
1
Number of Pages
X, 392
Number of Illustrations and Tables
26 b/w illustrations, 7 illustrations in colour
Topics