Methods in Molecular Biology

Cancer Epigenetics

Methods and Protocols

Editors: Dumitrescu, Ramona G., Verma, Mukesh (Eds.)

  • Includes epigenetic alterations that can be use in clinical practice
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
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Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-1-61779-612-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-61779-611-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The epigenetic regulation plays an important role in normal development and maintenance of tissue specific genes expression in humans and the disturbance of these patterns lead to changes involved in tumor formation. More recently, epigenetic changes have been observed in early stages of tumor development and together with the genetic alterations have been defined as abnormalities, necessary for cancer initiation and progression. In, Cancer Epigenetics: Methods and Protocols, expert researchers reviewed these epigenetics changes in different tumor types and described several technologies that are currently available to detect epigenetic changes. These technologies have lead to a better understanding of the processes in normal and cancerous cells. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.

Thorough and intuitive, Cancer Epigenetics: Methods and Protocols aids scientists in continuing to study epigenetic alterations  used in clinical practice as biomarkers of early cancerous lesions or markers of progression and prognosis.

Reviews

From the reviews:

“This book provides a clear description of the epigenetic changes in cancer that are important in early detection, progression, and prognosis, as well as the design of therapeutic tools necessary to combat cancer. … This is an excellent resource for scientists and oncologists interested in learning about currently available technologies to detect epigenetic changes that serve as biomarkers in detection of early cancerous lesions as well as markers of cancer progression and prognosis.” (Omer Iqbal, Doody’s Book Reviews, August, 2012)

Table of contents (29 chapters)

  • Epigenetic Markers of Early Tumor Development

    Dumitrescu, Ramona G.

    Pages 3-14

  • Epigenetics of Solid Cancer Stem Cells

    Mishra, Alok (et al.)

    Pages 15-31

  • DNA Methylation and Histone Modifications in Breast Cancer

    Dumitrescu, Ramona G.

    Pages 35-45

  • DNA Methylation Changes in Prostate Cancer

    Goering, Wolfgang (et al.)

    Pages 47-66

  • DNA Methylation in Promoter Region as Biomarkers in Prostate Cancer

    Yang, Mihi (et al.)

    Pages 67-109

Buy this book

eBook $139.00
price for USA (gross)
  • ISBN 978-1-61779-612-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.00
price for USA
  • ISBN 978-1-61779-611-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cancer Epigenetics
Book Subtitle
Methods and Protocols
Editors
  • Ramona G. Dumitrescu
  • Mukesh Verma
Series Title
Methods in Molecular Biology
Series Volume
863
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media, LLC
eBook ISBN
978-1-61779-612-8
DOI
10.1007/978-1-61779-612-8
Hardcover ISBN
978-1-61779-611-1
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XIII, 492
Number of Illustrations and Tables
10 b/w illustrations, 32 illustrations in colour
Topics