Methods in Molecular Biology

Homology Modeling

Methods and Protocols

Editors: Orry, Andrew J. W., Abagyan, Ruben (Eds.)

  • Describes each homology modeling steps from first principles
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
see more benefits

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-61779-588-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-61779-587-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.00
price for USA
  • ISBN 978-1-4939-5880-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Knowledge about protein tertiary structure can guide experiments, assist in the understanding of structure-function relationships, and aid the design of new therapeutics for disease. Homology modeling is an in silico method that predicts the tertiary structure of an amino acid sequence based on a homologous experimentally determined structure.  In, Homology Modelling: Methods and Protocols experts in the field describe each homology modeling step from first principles, provide case studies for challenging modeling targets and describe methods for the prediction of how other molecules such as drugs can interact with the protein. Written in the highly successful Methods in Molecular Biology™ series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.

 

Thorough and intuitive, Homology Modelling: Methods and Protocols guides scientists in the available homology modeling methods.

 

Table of contents (18 chapters)

  • Classification of Proteins: Available Structural Space for Molecular Modeling

    Andreeva, Antonina

    Pages 1-31

  • Effective Techniques for Protein Structure Mining

    Suhrer, Stefan J. (et al.)

    Pages 33-54

  • Methods for Sequence–Structure Alignment

    Venclovas, Česlovas

    Pages 55-82

  • Force Fields for Homology Modeling

    Bordner, Andrew J.

    Pages 83-106

  • Automated Protein Structure Modeling with SWISS-MODEL Workspace and the Protein Model Portal

    Bordoli, Lorenza (et al.)

    Pages 107-136

Buy this book

eBook $129.00
price for USA (gross)
  • ISBN 978-1-61779-588-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.00
price for USA
valid through November 5, 2017
  • ISBN 978-1-61779-587-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $169.00
price for USA
  • ISBN 978-1-4939-5880-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Homology Modeling
Book Subtitle
Methods and Protocols
Editors
  • Andrew J. W. Orry
  • Ruben Abagyan
Series Title
Methods in Molecular Biology
Series Volume
857
Copyright
2012
Publisher
Humana Press
Copyright Holder
Springer Science+Business Media,LLC
eBook ISBN
978-1-61779-588-6
DOI
10.1007/978-1-61779-588-6
Hardcover ISBN
978-1-61779-587-9
Softcover ISBN
978-1-4939-5880-1
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 419
Number of Illustrations and Tables
34 b/w illustrations, 55 illustrations in colour
Topics